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Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides

Pavel Anatol'evich Volkov 1
Pavel Anatol'evich Volkov
Svetlana Il'yasovna Verkhoturova 1
Svetlana Il'yasovna Verkhoturova
Svetlana Nikolaevna Arbuzova 1
Svetlana Nikolaevna Arbuzova
Kseniya Olegovna Khrapova 1
Kseniya Olegovna Khrapova
Ivan A. Bidusenko 1
Ivan A. Bidusenko
Sergei Victorovich Zinchenko 1
Sergei Victorovich Zinchenko
Boris Aleksandrovich Trofimov 1
Boris Aleksandrovich Trofimov
1 A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russian Federation
Published 2025-02-18
CommunicationVolume 35, Issue 2, 158-161
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Volkov P. A. et al. Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides // Mendeleev Communications. 2025. Vol. 35. No. 2. pp. 158-161.
GOST all authors (up to 50) Copy
Volkov P. A., Verkhoturova S. I., Arbuzova S. N., Khrapova K. O., Bidusenko I. A., Zinchenko S. V., Trofimov B. A. Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides // Mendeleev Communications. 2025. Vol. 35. No. 2. pp. 158-161.
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TY - JOUR
DO - 10.71267/mencom.7627
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7627
TI - Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides
T2 - Mendeleev Communications
AU - Volkov, Pavel Anatol'evich
AU - Verkhoturova, Svetlana Il'yasovna
AU - Arbuzova, Svetlana Nikolaevna
AU - Khrapova, Kseniya Olegovna
AU - Bidusenko, Ivan A.
AU - Zinchenko, Sergei Victorovich
AU - Trofimov, Boris Aleksandrovich
PY - 2025
DA - 2025/02/18
PB - Mendeleev Communications
SP - 158-161
IS - 2
VL - 35
ER -
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@article{2025_Volkov,
author = {Pavel Anatol'evich Volkov and Svetlana Il'yasovna Verkhoturova and Svetlana Nikolaevna Arbuzova and Kseniya Olegovna Khrapova and Ivan A. Bidusenko and Sergei Victorovich Zinchenko and Boris Aleksandrovich Trofimov},
title = {Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7627},
number = {2},
pages = {158--161},
doi = {10.71267/mencom.7627}
}
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Cite this
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Volkov, Pavel Anatol'evich, et al. “Extraordinary sulfur/oxygen exchange between P=S and C=O bonds during the reaction of γ-amino ynones ketones with secondary phosphine sulfides.” Mendeleev Communications, vol. 35, no. 2, Feb. 2025, pp. 158-161. https://mendcomm.colab.ws/publications/10.71267/mencom.7627.

Keywords

1
2-dihydro-3H-pyrrole-3-thiones
amino ynones
heterocyclization.
nucleophilic addition
secondary phosphine sulfides

Abstract

Unknown reactivity patterns of P=S and C=O bonds were observed when γ-amino α, β-ynones reacted with secondary phosphine sulfides affording, instead of the addition/ cyclization products, 1,2-dihydro-3H-pyrrole-3-thiones and the corresponding secondary phosphine oxides. The reaction mechanism involves the sulfur/oxygen exchange between the P=S and C=O functions. This is the first case of the successful competition between the P=S and P-H moieties as nucleophiles for electrophilic triple bond.

Funders

Ministry of Education and Science of the Russian Federation

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