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Pyrrolo[1,2-b]pyridazines: synthesis and application perspective

Elena Yur'evna Mendogralo 1
Elena Yur'evna Mendogralo
, 
Roman Olegovich Shcherbakov 1, 2
Roman Olegovich Shcherbakov
, 
Ludmila N. Sorotskaja 3
Ludmila N. Sorotskaja
, 
Maxim Grigorievich Uchuskin 1, 2
Maxim Grigorievich Uchuskin
1 Perm State University, 614990 Perm, Russian Federation
2 Perm Federal Scientific Centre, Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences, 614013 Perm, Russian Federation
3 Kuban State Technological University, 350072 Krasnodar, Russian Federation
10.71267/mencom.7749
Published 2025-03-31
Communication , Volume 35, Issue 3, 241-248
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Mendogralo E. Y. et al. Pyrrolo[1,2-b]pyridazines: synthesis and application perspective // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 241-248.
GOST all authors (up to 50) Copy
Mendogralo E. Y., Shcherbakov R. O., Sorotskaja L. N., Uchuskin M. G. Pyrrolo[1,2-b]pyridazines: synthesis and application perspective // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 241-248.
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TY - JOUR
DO - 10.71267/mencom.7749
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7749
TI - Pyrrolo[1,2-b]pyridazines: synthesis and application perspective
T2 - Mendeleev Communications
AU - Mendogralo, Elena Yur'evna
AU - Shcherbakov, Roman Olegovich
AU - Sorotskaja, Ludmila N.
AU - Uchuskin, Maxim Grigorievich
PY - 2025
DA - 2025/03/31
PB - Mendeleev Communications
SP - 241-248
IS - 3
VL - 35
ER -
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@article{2025_Mendogralo,
author = {Elena Yur'evna Mendogralo and Roman Olegovich Shcherbakov and Ludmila N. Sorotskaja and Maxim Grigorievich Uchuskin},
title = {Pyrrolo[1,2-b]pyridazines: synthesis and application perspective},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7749},
number = {3},
pages = {241--248},
doi = {10.71267/mencom.7749}
}
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Cite this
MLA Copy
Mendogralo, Elena Yur'evna, et al. “Pyrrolo[1,2-b]pyridazines: synthesis and application perspective.” Mendeleev Communications, vol. 35, no. 3, Mar. 2025, pp. 241-248. https://mendcomm.colab.ws/publications/10.71267/mencom.7749.

Keywords

1
2-b]pyridazines
3-dipolar cycloaddition
Cyclization
pyridazine
Pyrrole
pyrrolo[1
synthetic methodology

Abstract

Pyrrolo[1,2-b]pyridazines continue to attract significant interest due to their diverse biological activities. This review explores various synthetic approaches to constructing the pyrrolo[1,2-b]pyridazine scaffold and examines its applications. Covering key advancements in pyrrolo[1,2-b]pyridazine chemistry reported between 2008 and 2024, we highlight their role in the development of practically relevant compounds. By emphasizing recent progress in this field, we aim to inspire further research and innovation in the synthesis and application of these heterocyclic systems.

Funders

Russian Science Foundation
24-73-10099

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