Keywords
charge
cytotoxicity.
L-cysteine
nanoparticles
self-assembly
silver
size
Abstract
Polypeptide-like supramolecular aggregates are formed in aqueous cysteine-AgNO3 solution. At low pH, their positively charged shell consists of several layers of cysteine-Ag+ complexes held by hydrogen bonds; with an increase in pH, the particles aggregate at isoelectric point; while at higher pH, the shell acquires negative charge and starts being destroyed. The pH control has been demonstrated for cytotoxic effect of the solution against MCF-7 breast cancer cells
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