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Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine

Sergey Sergeyevich Lunkov 1, 2
Sergey Sergeyevich Lunkov
, 
Artem Andreevich Zemtsov 1
Artem Andreevich Zemtsov
, 
Vitalij Vladimirovich Levin 1
Vitalij Vladimirovich Levin
, 
2 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
10.1016/j.mencom.2023.04.028
Published 2023-04-13
Communication , Volume 33, Issue 3, 387-389
6
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Lunkov S. S. et al. Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine // Mendeleev Communications. 2023. Vol. 33. No. 3. pp. 387-389.
GOST all authors (up to 50) Copy
Lunkov S. S., Zemtsov A. A., Levin V. V., Dilman A. D. Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine // Mendeleev Communications. 2023. Vol. 33. No. 3. pp. 387-389.
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TY - JOUR
DO - 10.1016/j.mencom.2023.04.028
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.028
TI - Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine
T2 - Mendeleev Communications
AU - Lunkov, Sergey Sergeyevich
AU - Zemtsov, Artem Andreevich
AU - Levin, Vitalij Vladimirovich
AU - Dilman, Alexander Davidovich
PY - 2023
DA - 2023/04/13
PB - Mendeleev Communications
SP - 387-389
IS - 3
VL - 33
ER -
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@article{2023_Lunkov,
author = {Sergey Sergeyevich Lunkov and Artem Andreevich Zemtsov and Vitalij Vladimirovich Levin and Alexander Davidovich Dilman},
title = {Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.028},
number = {3},
pages = {387--389},
doi = {10.1016/j.mencom.2023.04.028}
}
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Lunkov, Sergey Sergeyevich, et al. “Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine.” Mendeleev Communications, vol. 33, no. 3, Apr. 2023, pp. 387-389. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.028.

Keywords

alcohols
deoxygenation
ethers.
organofluorine compounds
photocatalysis
radicals

Abstract

A new method for deoxygenation of fluoroalkyl-substituted alcohols involves derivatization of the hydroxy group with pentafluoropyridine followed by photoredox catalyzed reduction of the obtained hetaryl ethers using γ-terpinene as a source of hydrogen. The initial alcohols can be easily obtained by nucleophilic fluoroalkylation of the corresponding aldehydes.

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