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A simple synthesis of natural spinazarins and their analogues

Dmitry Nikolaevich Pelageev 1, 2
Dmitry Nikolaevich Pelageev
, 
Ksenia Leonidovna Borisova 1
Ksenia Leonidovna Borisova
, 
Svetlana Mikhailovna Kovach 2
Svetlana Mikhailovna Kovach
, 
Vyacheslav Valentinovich Makhankov 1
Vyacheslav Valentinovich Makhankov
, 
Victor Philippovich Anufriev 1
Victor Philippovich Anufriev
1 G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russian Federation
2 Institute of High Technologies and Advanced Materials, Far Eastern Federal University, Vladivostok, Russian Federation
10.1016/j.mencom.2023.02.026
Published 2023-02-13
Communication , Volume 33, Issue 2, 231-233
1
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Pelageev D. N. et al. A simple synthesis of natural spinazarins and their analogues // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 231-233.
GOST all authors (up to 50) Copy
Pelageev D. N., Borisova K. L., Kovach S. M., Makhankov V. V., Anufriev V. P. A simple synthesis of natural spinazarins and their analogues // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 231-233.
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TY - JOUR
DO - 10.1016/j.mencom.2023.02.026
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.026
TI - A simple synthesis of natural spinazarins and their analogues
T2 - Mendeleev Communications
AU - Pelageev, Dmitry Nikolaevich
AU - Borisova, Ksenia Leonidovna
AU - Kovach, Svetlana Mikhailovna
AU - Makhankov, Vyacheslav Valentinovich
AU - Anufriev, Victor Philippovich
PY - 2023
DA - 2023/02/13
PB - Mendeleev Communications
SP - 231-233
IS - 2
VL - 33
ER -
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@article{2023_Pelageev,
author = {Dmitry Nikolaevich Pelageev and Ksenia Leonidovna Borisova and Svetlana Mikhailovna Kovach and Vyacheslav Valentinovich Makhankov and Victor Philippovich Anufriev},
title = {A simple synthesis of natural spinazarins and their analogues},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.026},
number = {2},
pages = {231--233},
doi = {10.1016/j.mencom.2023.02.026}
}
MLA
Cite this
MLA Copy
Pelageev, Dmitry Nikolaevich, et al. “A simple synthesis of natural spinazarins and their analogues.” Mendeleev Communications, vol. 33, no. 2, Feb. 2023, pp. 231-233. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.026.

Keywords

2
3-dihydroxynaphthazarin
4-naphthoquinone
5
8-dihydroxy-1
hydrolysis
naphthazarin
organic azides
sea urchin pigments.
spinazarin

Abstract

A short simple synthesis of spinazarins (2,3-dihydroxy-naphthazarins or 2,3,5,8-tetrahydroxy-1,4-naphtho-quinones) from available 2,3-dichloronaphthazarin derivatives involves replacement of chlorine atoms with azido groups followed by their acidic hydrolysis. The procedure can be used for the preparative synthesis of natural biologically active spinazarins and their analogues.

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