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Synthesis of novel lipophilic tetraamines with cytotoxic activity

Ksenia Andreevna Perevoshchikova 1
Ksenia Andreevna Perevoshchikova
, 
Artemiy Igorevich Nichugovskiy 1
Artemiy Igorevich Nichugovskiy
, 
Alexandra Karenovna Isagulieva 2
Alexandra Karenovna Isagulieva
, 
Nina Georgievna Morozova 1
Nina Georgievna Morozova
, 
Igor Vladimirovich Ivanov 1
Igor Vladimirovich Ivanov
, 
Mikhail Aleksandrovich Maslov 1
Mikhail Aleksandrovich Maslov
, 
A A Shtil 2
A A Shtil
10.1016/j.mencom.2019.11.003
Published 2019-11-01
Communication , Volume 29, Issue 6, 616-618
7
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Perevoshchikova K. A. et al. Synthesis of novel lipophilic tetraamines with cytotoxic activity // Mendeleev Communications. 2019. Vol. 29. No. 6. pp. 616-618.
GOST all authors (up to 50) Copy
Perevoshchikova K. A., Nichugovskiy A. I., Isagulieva A. K., Morozova N. G., Ivanov I. V., Maslov M. A., Shtil A. A. Synthesis of novel lipophilic tetraamines with cytotoxic activity // Mendeleev Communications. 2019. Vol. 29. No. 6. pp. 616-618.
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TY - JOUR
DO - 10.1016/j.mencom.2019.11.003
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.11.003
TI - Synthesis of novel lipophilic tetraamines with cytotoxic activity
T2 - Mendeleev Communications
AU - Perevoshchikova, Ksenia Andreevna
AU - Nichugovskiy, Artemiy Igorevich
AU - Isagulieva, Alexandra Karenovna
AU - Morozova, Nina Georgievna
AU - Ivanov, Igor Vladimirovich
AU - Maslov, Mikhail Aleksandrovich
AU - Shtil, A A
PY - 2019
DA - 2019/11/01
PB - Mendeleev Communications
SP - 616-618
IS - 6
VL - 29
ER -
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@article{2019_Perevoshchikova,
author = {Ksenia Andreevna Perevoshchikova and Artemiy Igorevich Nichugovskiy and Alexandra Karenovna Isagulieva and Nina Georgievna Morozova and Igor Vladimirovich Ivanov and Mikhail Aleksandrovich Maslov and A A Shtil},
title = {Synthesis of novel lipophilic tetraamines with cytotoxic activity},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.11.003},
number = {6},
pages = {616--618},
doi = {10.1016/j.mencom.2019.11.003}
}
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Perevoshchikova, Ksenia Andreevna, et al. “Synthesis of novel lipophilic tetraamines with cytotoxic activity.” Mendeleev Communications, vol. 29, no. 6, Nov. 2019, pp. 616-618. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.11.003.

Abstract

New lipophilic polyamines in which natural or synthetic tetraamines were linked via the terminal NH2 groups to diglycerides and/or to short-chained aliphatic substituents were synthesized, and their cytotoxic activity was tested. Relationship between the structure of the synthesized compounds and their cytotoxicity and hemolytic effect was evaluated.

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