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Steric shielding enables slow exchange in DMSO: a BODIPY–cyanurate platform

Alexander A Goncharenko 1, 2
Alexander A Goncharenko
, 
Daniil N Finogenov 1
Daniil N Finogenov
, 
Alexander Andreevich Ksenofontov 2
Alexander Andreevich Ksenofontov
, 
Viktor V Aleksandriiskii 1
Viktor V Aleksandriiskii
, 
Elena Vladimirovna Antina 2
Elena Vladimirovna Antina
,  , 
Alexander A Kalyagin 2
Alexander A Kalyagin
1 Institute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology, 153000 Ivanovo, Russian Federation
10.71267/mencom.8081
Published 23 September 2026
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Goncharenko A. A. et al. Steric shielding enables slow exchange in DMSO: a BODIPY–cyanurate platform // Mendeleev Communications. 2026.
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Goncharenko A. A., Finogenov D. N., Ksenofontov A. A., Aleksandriiskii V. V., Antina E. V., Stuzhin P. A., Kalyagin A. A. Steric shielding enables slow exchange in DMSO: a BODIPY–cyanurate platform // Mendeleev Communications. 2026.
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TY - JOUR
DO - 10.71267/mencom.8081
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.8081
TI - Steric shielding enables slow exchange in DMSO: a BODIPY–cyanurate platform
T2 - Mendeleev Communications
AU - Goncharenko, Alexander A
AU - Finogenov, Daniil N
AU - Ksenofontov, Alexander Andreevich
AU - Aleksandriiskii, Viktor V
AU - Antina, Elena Vladimirovna
AU - Stuzhin, Pavel Anatolievich
AU - Kalyagin, Alexander A
PY - 2026
DA - 2026/09/23
PB - Mendeleev Communications
ER -
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@article{2026_Goncharenko,
author = {Alexander A Goncharenko and Daniil N Finogenov and Alexander Andreevich Ksenofontov and Viktor V Aleksandriiskii and Elena Vladimirovna Antina and Pavel Anatolievich Stuzhin and Alexander A Kalyagin},
title = {Steric shielding enables slow exchange in DMSO: a BODIPY–cyanurate platform},
journal = {Mendeleev Communications},
year = {2026},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.8081},
doi = {10.71267/mencom.8081}
}
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Keywords

BODIPY
complexation
cyanuric derivatives
fluorescence
NMR study
tautomerism

Abstract

A BODIPY–cyanurate conjugate featuring an O–aryl linkage was designed to probe supramolecular tautomerism in competitive solvents. At analytical concentrations, association and complexation are suppressed, revealing an intrinsic concentration dependence that limits fluorescence sensing while validating the design strategy. This work demonstrates that bulky hydrophobic scaffolds enable kinetic stabilization of supramolecular assemblies in polar media, providing a foundational principle for future receptor development.

Funders

Russian Science Foundation
24-73-00309

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