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Half-sandwich nickel(II) hydride complexes as efficient precatalysts for the alkylation of furan derivatives with olefins

Olga Valerievna Khazipova 1
Olga Valerievna Khazipova
, 
Alexander Petrovich Savost'yanov 1
Alexander Petrovich Savost'yanov
, 
Oleg Vladimirovich Khazipov 1
Oleg Vladimirovich Khazipov
, 
Konstantin Evgen'evich Shepelenko 1, 2
Konstantin Evgen'evich Shepelenko
, 
Viktor Mikhailovich Chernyshev 1, 2
Viktor Mikhailovich Chernyshev
2 Skolkovo Institute of Science and Technology, 121205 Moscow, Russian Federation
10.71267/mencom.8076
Published 23 September 2026
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Khazipova O. V. et al. Half-sandwich nickel(II) hydride complexes as efficient precatalysts for the alkylation of furan derivatives with olefins // Mendeleev Communications. 2026.
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Khazipova O. V., Savost'yanov A. P., Khazipov O. V., Shepelenko K. E., Chernyshev V. M. Half-sandwich nickel(II) hydride complexes as efficient precatalysts for the alkylation of furan derivatives with olefins // Mendeleev Communications. 2026.
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TY - JOUR
DO - 10.71267/mencom.8076
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.8076
TI - Half-sandwich nickel(II) hydride complexes as efficient precatalysts for the alkylation of furan derivatives with olefins
T2 - Mendeleev Communications
AU - Khazipova, Olga Valerievna
AU - Savost'yanov, Alexander Petrovich
AU - Khazipov, Oleg Vladimirovich
AU - Shepelenko, Konstantin Evgen'evich
AU - Chernyshev, Viktor Mikhailovich
PY - 2026
DA - 2026/09/23
PB - Mendeleev Communications
ER -
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@article{2026_Khazipova,
author = {Olga Valerievna Khazipova and Alexander Petrovich Savost'yanov and Oleg Vladimirovich Khazipov and Konstantin Evgen'evich Shepelenko and Viktor Mikhailovich Chernyshev},
title = {Half-sandwich nickel(II) hydride complexes as efficient precatalysts for the alkylation of furan derivatives with olefins},
journal = {Mendeleev Communications},
year = {2026},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.8076},
doi = {10.71267/mencom.8076}
}
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Keywords

alkylation
catalysis
cyclopentadienyl
N-heterocyclic carbene
nickel hydride complexes

Abstract

A new class of thermally activated nickel(ii) hydride precatalysts, (NHC)Ni(H)Cp, was employed in the C2-selective alkylation of furan derivatives with olefins. These well-defined complexes operated without external reducing agents such as sodium formate, thereby avoiding stoichiometric by-products. The use of optimal IMes-ligated complex afforded various alkylated furans in high to excellent yields with complete regioselectivity, broad substrate scope, and operational simplicity, representing a practical and sustainable alternative for biomass-derived furan functionalization.

Funders

Russian Science Foundation
24-43-00081

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Khazipova Olga Valerievna, Savost'yanov Alexander Petrovich, Khazipov Oleg Vladimirovich, Chernyshev Viktor Mikhailovich
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