Home / Articles / Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines

Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines

Anatolii Savel'evich Morkovnik 1
Anatolii Savel'evich Morkovnik
, 
Alexander Aleksandrovich Zubenko 2
Alexander Aleksandrovich Zubenko
, 
Vadim Sergeyevich Sochnev 1, 3
Vadim Sergeyevich Sochnev
, 
Lyudmila Nikolaevna Divaeva 1
Lyudmila Nikolaevna Divaeva
, 
Alexander Ivanovich Klimenko 2
Alexander Ivanovich Klimenko
,  , 
Viktorya Vladimirovna Chekrysheva 2
Viktorya Vladimirovna Chekrysheva
, 
Alexandra Evgen'evna Svyatogorova 2
Alexandra Evgen'evna Svyatogorova
2 North-Caucasian Zonal Research Veterinary Institute, Federal Rostov Agricultural Research Centre, 346406 Novocherkassk, Russian Federation
3 Rostov State Medical University, 344022 Rostov-on-Don, Russian Federation
10.71267/mencom.8038
Published 23 September 2026
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Morkovnik A. S. et al. Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines // Mendeleev Communications. 2026.
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Morkovnik A. S., Zubenko A. A., Sochnev V. S., Divaeva L. N., Klimenko A. I., Demidov O. P., Chekrysheva V. V., Svyatogorova A. E. Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines // Mendeleev Communications. 2026.
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TY - JOUR
DO - 10.71267/mencom.8038
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.8038
TI - Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines
T2 - Mendeleev Communications
AU - Morkovnik, Anatolii Savel'evich
AU - Zubenko, Alexander Aleksandrovich
AU - Sochnev, Vadim Sergeyevich
AU - Divaeva, Lyudmila Nikolaevna
AU - Klimenko, Alexander Ivanovich
AU - Demidov, Oleg Petrovich
AU - Chekrysheva, Viktorya Vladimirovna
AU - Svyatogorova, Alexandra Evgen'evna
PY - 2026
DA - 2026/09/23
PB - Mendeleev Communications
ER -
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@article{2026_Morkovnik,
author = {Anatolii Savel'evich Morkovnik and Alexander Aleksandrovich Zubenko and Vadim Sergeyevich Sochnev and Lyudmila Nikolaevna Divaeva and Alexander Ivanovich Klimenko and Oleg Petrovich Demidov and Viktorya Vladimirovna Chekrysheva and Alexandra Evgen'evna Svyatogorova},
title = {Glaucine-exemplified annulation of pyrrole ring as a route from aporphines to pyrroloaporphines},
journal = {Mendeleev Communications},
year = {2026},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.8038},
doi = {10.71267/mencom.8038}
}
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Keywords

Annulation
aporphines
dibenzo[de,g]pyrrolo[3,2,1-ij]quinolines
glaucine
pyrroloaporphines
quantum chemical calculations

Abstract

A novel two-step transformation of aporphines into pyrroloaporphine derivatives is described with an example of model glaucine. The key step constitutes the 6,7-peri annulation of pyrrole ring onto the aporphine core.

Funders

Ministry of Education and Science of the Russian Federation
FENW 2026-0018

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