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Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids

Sergei A. Serkov 1
Sergei A. Serkov
, 
Natalya V. Sigay 1
Natalya V. Sigay
, 
Natalya N. Kostikova 1
Natalya N. Kostikova
, 
Natalya Georgievna Kolotyrkina 1
Natalya Georgievna Kolotyrkina
, 
Galina Anatol'evna Gazieva 1
Galina Anatol'evna Gazieva
10.71267/mencom.7922
Published 2026-03-24
Communication , Volume 36, Issue 3, 335-337
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Serkov S. A. et al. Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids // Mendeleev Communications. 2026. Vol. 36. No. 3. pp. 335-337.
GOST all authors (up to 50) Copy
Serkov S. A., Sigay N. V., Kostikova N. N., Kolotyrkina N. G., Gazieva G. A. Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids // Mendeleev Communications. 2026. Vol. 36. No. 3. pp. 335-337.
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TY - JOUR
DO - 10.71267/mencom.7922
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7922
TI - Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids
T2 - Mendeleev Communications
AU - Serkov, Sergei A.
AU - Sigay, Natalya V.
AU - Kostikova, Natalya N.
AU - Kolotyrkina, Natalya Georgievna
AU - Gazieva, Galina Anatol'evna
PY - 2026
DA - 2026/03/24
PB - Mendeleev Communications
SP - 335-337
IS - 3
VL - 36
ER -
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@article{2026_Serkov,
author = {Sergei A. Serkov and Natalya V. Sigay and Natalya N. Kostikova and Natalya Georgievna Kolotyrkina and Galina Anatol'evna Gazieva},
title = {Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids},
journal = {Mendeleev Communications},
year = {2026},
volume = {36},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7922},
number = {3},
pages = {335--337},
doi = {10.71267/mencom.7922}
}
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Serkov, Sergei A., et al. “Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids.” Mendeleev Communications, vol. 36, no. 3, Mar. 2026, pp. 335-337. https://mendcomm.colab.ws/publications/10.71267/mencom.7922.
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Keywords

anthranilamide
anthranilhydrazide
benzo[e]pyrrolo[1,2-b][1,2,4]triazepine
heterocyclization
itaconic acid
pyrrolo[1,2-a]quinazoline

Abstract

Two new heterocyclic carboxylic acids, namely, 2-carboxy derivatives of naturally occurring 2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one and potentially biologically active 2,3-dihydro-1H-benzo[e]pyrrolo[1,2-b][1,2,4]triazepin-6(5H)-one, have been synthesized by the fusion of itaconic acid with anthranilic acid amide or hydrazide, respectively, in one or two steps in moderate to high yields.

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