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Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids

Chengqun Chen 1
Chengqun Chen
, 
Kexin Ren 1
Kexin Ren
1 Department of Chemical Engineering, Fuzhou University Zhicheng College, 350108 Fuzhou, P. R. China
10.71267/mencom.7917
Published 2026-02-03
Communication , Volume 36, Issue 2, 183-185
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Chen C., Ren K. Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids // Mendeleev Communications. 2026. Vol. 36. No. 2. pp. 183-185.
GOST all authors (up to 50) Copy
Chen C., Ren K. Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids // Mendeleev Communications. 2026. Vol. 36. No. 2. pp. 183-185.
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TY - JOUR
DO - 10.71267/mencom.7917
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7917
TI - Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids
T2 - Mendeleev Communications
AU - Chen, Chengqun
AU - Ren, Kexin
PY - 2026
DA - 2026/02/03
PB - Mendeleev Communications
SP - 183-185
IS - 2
VL - 36
ER -
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@article{2026_Chen,
author = {Chengqun Chen and Kexin Ren},
title = {Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids},
journal = {Mendeleev Communications},
year = {2026},
volume = {36},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7917},
number = {2},
pages = {183--185},
doi = {10.71267/mencom.7917}
}
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Chen, Chengqun, and Kexin Ren. “Metal-free synthesis of 4-methylthio-3,4-dihydroisocoumarins from 2-(2-arylvinyl)benzoic acids.” Mendeleev Communications, vol. 36, no. 2, Feb. 2026, pp. 183-185. https://mendcomm.colab.ws/publications/10.71267/mencom.7917.

Keywords

2-(2-arylvinyl)benzoic acid
dihydroisocoumarin
metal-free
methylthio compounds

Abstract

Herein we report a straightforward and efficient procedure for synthesizing 4-methylthio-3,4-dihydroisocoumarins. The method involves reacting 2-(2-arylvinyl)benzoic acids with dimethyl(methylthio)sulfonium trifluoromethanesulfonate under mild, metal-free conditions.

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