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Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds

Anh Thi Tuyet Dang 1
Anh Thi Tuyet Dang
, 
Nhung Thi Dao 2
Nhung Thi Dao
, 
Dat T Nguyen 2
Dat T Nguyen
, 
Alexander A Titov 3
Alexander A Titov
, 
Hanh Thi My Luong 2
Hanh Thi My Luong
, 
Victor Nikolaevich Khrustalev 3, 4
Victor Nikolaevich Khrustalev
, 
Van T.T. Tran 2
Van T.T. Tran
, 
Anh Tuan Le 2
Anh Tuan Le
1 Institute of Chemistry, Vietnam Academy of Science and Technology, 100000 Hanoi, Vietnam
2 Faculty of Chemistry, University of Science, Vietnam National University, 11021 Hanoi, Vietnam
10.71267/mencom.7911
Published 4 June 2026 , received 8 September 2025
Communication , Volume 36, Issue 4, 460-462
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Dang A. T. T. et al. Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds // Mendeleev Communications. 2026. Vol. 36. No. 4. pp. 460-462.
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Dang A. T. T., Dao N. T., Nguyen D. T., Titov A. A., Luong H. T. M., Khrustalev V. N., Tran V. T., Le A. T. Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds // Mendeleev Communications. 2026. Vol. 36. No. 4. pp. 460-462.
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TY - JOUR
DO - 10.71267/mencom.7911
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7911
TI - Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds
T2 - Mendeleev Communications
AU - Dang, Anh Thi Tuyet
AU - Dao, Nhung Thi
AU - Nguyen, Dat T
AU - Titov, Alexander A
AU - Luong, Hanh Thi My
AU - Khrustalev, Victor Nikolaevich
AU - Tran, Van T.T.
AU - Le, Anh Tuan
PY - 2026
DA - 2026/06/04
PB - Mendeleev Communications
SP - 460-462
IS - 4
VL - 36
ER -
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@article{2026_Dang,
author = {Anh Thi Tuyet Dang and Nhung Thi Dao and Dat T Nguyen and Alexander A Titov and Hanh Thi My Luong and Victor Nikolaevich Khrustalev and Van T.T. Tran and Anh Tuan Le},
title = {Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds},
journal = {Mendeleev Communications},
year = {2026},
volume = {36},
publisher = {Mendeleev Communications},
month = {Jun},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7911},
number = {4},
pages = {460--462},
doi = {10.71267/mencom.7911}
}
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Dang, Anh Thi Tuyet, et al. “Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds.” Mendeleev Communications, vol. 36, no. 4, Jun. 2026, pp. 460-462. https://mendcomm.colab.ws/publications/10.71267/mencom.7911.
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Keywords

aza-14-crown-4 compounds
piperidone
Soldatenkov’s modification
tetracyclic compounds
X-ray study

Abstract

New aza-14-crown-4 compounds incorporating γ-piperidone unit have been prepared through the three-component reaction between dialdehyde podand, a ketone with two active methylene groups, and ammonium acetate or 2-phenylethylamine as nitrogen sources. Based on X-ray study, configuration of the products has been determined as rac-1S,21R,22S,24R.

Funders

Russian Science Foundation
24-43-04003

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