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Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids

Luyao Wang 1
Luyao Wang
, 
Shanshan Huang 1
Shanshan Huang
, 
Yonghong Du 1
Yonghong Du
, 
Xintong Yang 1
Xintong Yang
, 
Sirui Kong 1
Sirui Kong
, 
Ruihan Gao 1
Ruihan Gao
, 
Jinjing Li 1
Jinjing Li
1 College of Pharmacy, Jiamusi University, 15400 Jiamusi, China
10.71267/mencom.7903
Published 2026-03-24
Communication , Volume 36, Issue 3, 332-334
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Wang L. et al. Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids // Mendeleev Communications. 2026. Vol. 36. No. 3. pp. 332-334.
GOST all authors (up to 50) Copy
Wang L., Huang S., Du Y., Yang X., Kong S., Gao R., Li J. Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids // Mendeleev Communications. 2026. Vol. 36. No. 3. pp. 332-334.
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TY - JOUR
DO - 10.71267/mencom.7903
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7903
TI - Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids
T2 - Mendeleev Communications
AU - Wang, Luyao
AU - Huang, Shanshan
AU - Du, Yonghong
AU - Yang, Xintong
AU - Kong, Sirui
AU - Gao, Ruihan
AU - Li, Jinjing
PY - 2026
DA - 2026/03/24
PB - Mendeleev Communications
SP - 332-334
IS - 3
VL - 36
ER -
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@article{2026_Wang,
author = {Luyao Wang and Shanshan Huang and Yonghong Du and Xintong Yang and Sirui Kong and Ruihan Gao and Jinjing Li},
title = {Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids},
journal = {Mendeleev Communications},
year = {2026},
volume = {36},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7903},
number = {3},
pages = {332--334},
doi = {10.71267/mencom.7903}
}
MLA
Cite this
MLA Copy
Wang, Luyao, et al. “Design, synthesis and antitumor activity of new s-triazine--2-hydroxybenzophenone hybrids.” Mendeleev Communications, vol. 36, no. 3, Mar. 2026, pp. 332-334. https://mendcomm.colab.ws/publications/10.71267/mencom.7903.

Keywords

s-triazine
antitumor activity
benzophenones
Friedel–Crafts reaction
MTT method

Abstract

2-Hydroxybenzophenones synthesized via the Friedel–Crafts reaction between the properly substituted phenols and benzoyl chlorides were then O-alkylated with mono/disubstituted cyanuric chlorides. The substituent choice was guided by the principle of active substructure splicing. The thus obtained sixteen s-triazine–2-hydroxybenzophenone hybrids were assessed in vitro using the MTT assay.

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