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Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides

Tatyana B. Anisimova 1
Tatyana B. Anisimova
, 
Maria V. Kashina 2
Maria V. Kashina
, 
Mikhail A. Kinzhalov 2
Mikhail A. Kinzhalov
, 
M. Fátima С. Guedes da Silva 1
M. Fátima С. Guedes da Silva
, 
Armando J. L. Pombeiro 1
Armando J. L. Pombeiro
, 
Konstantin V. Luzyanin 3
Konstantin V. Luzyanin
1 Centro de Química Estrutural, Instituto Supérior Técnico, Universidade de Lisboa, 1049-001 Lisbon, Portugal
3 Department of Chemistry, University of Liverpool, L69 7ZD Liverpool, United Kingdom
10.71267/mencom.7888
Published 2026-02-03
Communication , Volume 36, Issue 2, 135-137
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Anisimova T. B. et al. Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides // Mendeleev Communications. 2026. Vol. 36. No. 2. pp. 135-137.
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Anisimova T. B., Kashina M. V., Kinzhalov M. A., Guedes da Silva M. F. С., Pombeiro A. J. L., Luzyanin K. V. Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides // Mendeleev Communications. 2026. Vol. 36. No. 2. pp. 135-137.
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TY - JOUR
DO - 10.71267/mencom.7888
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7888
TI - Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides
T2 - Mendeleev Communications
AU - Anisimova, Tatyana B.
AU - Kashina, Maria V.
AU - Kinzhalov, Mikhail A.
AU - Guedes da Silva, M. Fátima С.
AU - Pombeiro, Armando J. L.
AU - Luzyanin, Konstantin V.
PY - 2026
DA - 2026/02/03
PB - Mendeleev Communications
SP - 135-137
IS - 2
VL - 36
ER -
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@article{2026_Anisimova,
author = {Tatyana B. Anisimova and Maria V. Kashina and Mikhail A. Kinzhalov and M. Fátima С. Guedes da Silva and Armando J. L. Pombeiro and Konstantin V. Luzyanin},
title = {Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides},
journal = {Mendeleev Communications},
year = {2026},
volume = {36},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7888},
number = {2},
pages = {135--137},
doi = {10.71267/mencom.7888}
}
MLA
Cite this
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Anisimova, Tatyana B., et al. “Chiral acyclic diaminocarbene complexes of palladium(II), platinum(II) and gold(I) from metal-mediated coupling of isocyanides with chiral amino acid amides.” Mendeleev Communications, vol. 36, no. 2, Feb. 2026, pp. 135-137. https://mendcomm.colab.ws/publications/10.71267/mencom.7888.
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Keywords

amino acid amides
aminocarbene complexes
chiral complexes
gold complexes
isocyanide complexes
Palladium complexes
platinum complexes

Abstract

The reaction between enantiopure amino acid amides and metal-coordinated isocyanides such as cis-[Cl2M(CNR)2] (M = Pd, Pt) and [ClAu(CNR)] affords chiral acyclic diaminocarbene complexes in 64 to 91% yields with full retention of configuration at stereogenic centers. Structural analysis of the representative PdII complexes revealed isostructural enantiomeric pairs with slightly distorted square-planar geometry, featuring labile Pd–Cl bonds trans to the ADC ligand.

Funders

Russian Science Foundation
25-13-20028

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