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Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives

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10.71267/mencom.7868
Published 2025-11-29
Communication , Volume 36, Issue 1, 63-65
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Buravchenko G. I., Shchekotikhin A. E. Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives // Mendeleev Communications. 2025. Vol. 36. No. 1. pp. 63-65.
GOST all authors (up to 50) Copy
Buravchenko G. I., Shchekotikhin A. E. Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives // Mendeleev Communications. 2025. Vol. 36. No. 1. pp. 63-65.
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TY - JOUR
DO - 10.71267/mencom.7868
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7868
TI - Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives
T2 - Mendeleev Communications
AU - Buravchenko, Galina I
AU - Shchekotikhin, Andrey Egorovich
PY - 2025
DA - 2025/11/29
PB - Mendeleev Communications
SP - 63-65
IS - 1
VL - 36
ER -
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@article{2025_Buravchenko,
author = {Galina I Buravchenko and Andrey Egorovich Shchekotikhin},
title = {Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives},
journal = {Mendeleev Communications},
year = {2025},
volume = {36},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7868},
number = {1},
pages = {63--65},
doi = {10.71267/mencom.7868}
}
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Buravchenko, Galina I., and Andrey Egorovich Shchekotikhin. “Synthesis of 2-sulfamoylquinoxaline 1,4-dioxide derivatives.” Mendeleev Communications, vol. 36, no. 1, Nov. 2025, pp. 63-65. https://mendcomm.colab.ws/publications/10.71267/mencom.7868.

Keywords

2-oxo-2-phenylethane-1-sulfonamide
4-dioxides
Beirut reaction
nucleophilic substitution.
quinoxaline 1
sulfonamides

Abstract

An access to new sulfonamide-containing 3-phenylquinoxaline 1,4-dioxides has been accomplished via the Beirut reaction of benzofuroxans with N-(tert-butyl)-2-oxo-2-phenylethane-1-sulfonamide. The reaction of 5-aminobenzofuroxan derivatives afforded 7-amino-2-sulfamoylquinoxaline 1,4-dioxides, whereas nucleophilic substitution of the chlorine atom in 6,7-dichloro-2-sulfamoylquinoxaline 1,4-dioxide gave the corresponding 6-amino-substituted analogs.

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