Keywords
laser flash photolysis
photoactivated chemotherapy
photochemistry
photodynamic therapy
photophysics
platinum complexes
primary processes
rhodium complexes
ruthenium complexes
ultrafast spectroscopy
Abstract
Platinum group metal complexes are considered promising prodrugs for photoactivated chemotherapy (PACT), which is being developed as an oxygen-independent variant of photodynamic therapy (PDT) for malignant tumors. Primary photophysical and photochemical processes involving light-activated anticancer complexes of platinum, ruthenium and rhodium on timescales from hundreds of femtoseconds to hours are reviewed.
Funders
Russian Science Foundation
23-13-00226
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