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Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides

Lyudmila Vyacheslavovna Afanas'eva 1
Lyudmila Vyacheslavovna Afanas'eva
, 
Dzul'etta Vagenakovna Avetisyan 1
Dzul'etta Vagenakovna Avetisyan
,  ,  , 
Maksim Vladimirovich Andreev 1
Maksim Vladimirovich Andreev
, 
Vladimir Vasil'evich Burlakov 1 *
Vladimir Vasil'evich Burlakov
* vvburl@ineos.ac.ru
10.71267/mencom.7799
Published 2025-11-29
Communication , Volume 36, Issue 1, 61-62
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Afanas'eva L. V. et al. Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides // Mendeleev Communications. 2025. Vol. 36. No. 1. pp. 61-62.
GOST all authors (up to 50) Copy
Afanas'eva L. V., Avetisyan D. V., Artyushin O. I., Smirnova E. V., Andreev M. V., Burlakov V. V. Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides // Mendeleev Communications. 2025. Vol. 36. No. 1. pp. 61-62.
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TY - JOUR
DO - 10.71267/mencom.7799
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7799
TI - Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides
T2 - Mendeleev Communications
AU - Afanas'eva, Lyudmila Vyacheslavovna
AU - Avetisyan, Dzul'etta Vagenakovna
AU - Artyushin, Oleg Ivanovich
AU - Smirnova, Ekaterina V
AU - Andreev, Maksim Vladimirovich
AU - Burlakov, Vladimir Vasil'evich
PY - 2025
DA - 2025/11/29
PB - Mendeleev Communications
SP - 61-62
IS - 1
VL - 36
ER -
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@article{2025_Afanas'eva,
author = {Lyudmila Vyacheslavovna Afanas'eva and Dzul'etta Vagenakovna Avetisyan and Oleg Ivanovich Artyushin and Ekaterina V Smirnova and Maksim Vladimirovich Andreev and Vladimir Vasil'evich Burlakov},
title = {Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides},
journal = {Mendeleev Communications},
year = {2025},
volume = {36},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7799},
number = {1},
pages = {61--62},
doi = {10.71267/mencom.7799}
}
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Afanas'eva, Lyudmila Vyacheslavovna, et al. “Regioselective synthesis of novel derivatives of neo oxo carboxylic acids with two different functional groups from linear carboxylic acid chlorides.” Mendeleev Communications, vol. 36, no. 1, Nov. 2025, pp. 61-62. https://mendcomm.colab.ws/publications/10.71267/mencom.7799.

Keywords

bifunctional compounds
C–H functionalization
carbon monoxide
linear carboxylic acid chlorides
neo-alkanoic compounds
oxo carboxylic acids
superelectrophilic complex

Abstract

A selective ‘one-pot’ method has been developed for the synthesis of derivatives of neo oxo carboxylic acids with two different remote functional groups from linear acid chlorides, carbon monoxide, and two different nucleophiles. The transformation is promoted by the superelectrophilic system CBr4·2AlBr3. No other systems initiate such transformations.

Funders

Ministry of Education and Science of the Russian Federation
075-00276-25-00

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