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Determination of critical micelle concentrations of Pluronics

,  , 
Nikolay Sergeevich Melik-Nubarov 1
Nikolay Sergeevich Melik-Nubarov
, 
Irina Dmitrievna Grozdova 1
Irina Dmitrievna Grozdova
10.71267/mencom.7689
Published 2025-05-21
Communication , Volume 35, Issue 4, 437-439
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Iakimov N. P. et al. Determination of critical micelle concentrations of Pluronics // Mendeleev Communications. 2025. Vol. 35. No. 4. pp. 437-439.
GOST all authors (up to 50) Copy
Iakimov N. P., Fomin E. O., Melik-Nubarov N. S., Grozdova I. D. Determination of critical micelle concentrations of Pluronics // Mendeleev Communications. 2025. Vol. 35. No. 4. pp. 437-439.
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TY - JOUR
DO - 10.71267/mencom.7689
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7689
TI - Determination of critical micelle concentrations of Pluronics
T2 - Mendeleev Communications
AU - Iakimov, Nikolai Petrovich
AU - Fomin, Evgenii Olegovich
AU - Melik-Nubarov, Nikolay Sergeevich
AU - Grozdova, Irina Dmitrievna
PY - 2025
DA - 2025/05/21
PB - Mendeleev Communications
SP - 437-439
IS - 4
VL - 35
ER -
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@article{2025_Iakimov,
author = {Nikolai Petrovich Iakimov and Evgenii Olegovich Fomin and Nikolay Sergeevich Melik-Nubarov and Irina Dmitrievna Grozdova},
title = {Determination of critical micelle concentrations of Pluronics},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {May},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7689},
number = {4},
pages = {437--439},
doi = {10.71267/mencom.7689}
}
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Iakimov, Nikolai Petrovich, et al. “Determination of critical micelle concentrations of Pluronics.” Mendeleev Communications, vol. 35, no. 4, May. 2025, pp. 437-439. https://mendcomm.colab.ws/publications/10.71267/mencom.7689.

Keywords

1
3
5-hexatriene (DPH) fluorescence
6-diphenyl-1
critical micelle concentration
liposome–micelle lipid migration.
multidrug resistance
Pluronics

Abstract

Critical micelle concentrations (CMCs) of Pluronics were determined by three techniques, namely 1,6-diphenyl-1,3,5-hexatriene fluorescence, sensitization of multidrug-resistant cancer cells with Pluronic unimers and a novel technique based on the migration of fluorophore-labeled lipid from liposomes into Pluronic micelles. The CMCs of each Pluronic determined by the three methods differ by no more than 30% and are consistent with data reported by different research teams. A literature review revealed a widely cited dataset of CMC values that differ significantly from data reported by other research groups, including ours.

Funders

project ‘Contemporary Problems of Chemistry and Physical Chemistry of Macromolecules’
State Assignment no. AAAA-A21-121011990022-4

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