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An efficient solvent-free thiocyanation of indoles by grinding

Liang Wang 1
Liang Wang
, 
Dan Wang 1
Dan Wang
, 
Jie Tang 1
Jie Tang
1 School of Chemical and Pharmaceutical Engineering, Changzhou Vocational Institute of Engineering, 213164 Changzhou, P. R. China
10.71267/mencom.7677
Published 2025-03-31
Communication , Volume 35, Issue 3, 269-270
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Wang L., Wang D., Tang J. An efficient solvent-free thiocyanation of indoles by grinding // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 269-270.
GOST all authors (up to 50) Copy
Wang L., Wang D., Tang J. An efficient solvent-free thiocyanation of indoles by grinding // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 269-270.
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TY - JOUR
DO - 10.71267/mencom.7677
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7677
TI - An efficient solvent-free thiocyanation of indoles by grinding
T2 - Mendeleev Communications
AU - Wang, Liang
AU - Wang, Dan
AU - Tang, Jie
PY - 2025
DA - 2025/03/31
PB - Mendeleev Communications
SP - 269-270
IS - 3
VL - 35
ER -
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@article{2025_Wang,
author = {Liang Wang and Dan Wang and Jie Tang},
title = {An efficient solvent-free thiocyanation of indoles by grinding},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7677},
number = {3},
pages = {269--270},
doi = {10.71267/mencom.7677}
}
MLA
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MLA Copy
Wang, Liang, et al. “An efficient solvent-free thiocyanation of indoles by grinding.” Mendeleev Communications, vol. 35, no. 3, Mar. 2025, pp. 269-270. https://mendcomm.colab.ws/publications/10.71267/mencom.7677.

Keywords

ammonium thiocyanate.
grinding
hypervalent iodine(III) reagent
indole
solvent-free
thiocyanation

Abstract

An efficient thiocyanation of indoles by grinding with ammonium thiocyanate and hypervalent iodine reagents under solvent-free conditions has been developed. The reaction proceeded rapidly to provide the target 3-thiocyanatoindoles in 75--86% yields.

Funders

‘333’ Highlevel Talent Project of Jiangsu Province, and Academic Leader Research Fund of Changzhou Vocational Institute of Engineering

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