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Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide

Vadim Evgenievich Filatov 1, 2
Vadim Evgenievich Filatov
, 
Dmitrii Aleksandrovich Iuzabchuk 1
Dmitrii Aleksandrovich Iuzabchuk
, 
Dmitry Alexandrovich Guk 1
Dmitry Alexandrovich Guk
, 
Dmitrii Anatol'evich Lemenovskii 1
Dmitrii Anatol'evich Lemenovskii
, 
Elena Kimovna Beloglazkina 1
Elena Kimovna Beloglazkina
10.71267/mencom.7646
Published 2025-03-31
Communication , Volume 35, Issue 3, 341-343
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Filatov V. E. et al. Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 341-343.
GOST all authors (up to 50) Copy
Filatov V. E., Iuzabchuk D. A., Guk D. A., Lemenovskii D. A., Beloglazkina E. K. Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide // Mendeleev Communications. 2025. Vol. 35. No. 3. pp. 341-343.
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TY - JOUR
DO - 10.71267/mencom.7646
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7646
TI - Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide
T2 - Mendeleev Communications
AU - Filatov, Vadim Evgenievich
AU - Iuzabchuk, Dmitrii Aleksandrovich
AU - Guk, Dmitry Alexandrovich
AU - Lemenovskii, Dmitrii Anatol'evich
AU - Beloglazkina, Elena Kimovna
PY - 2025
DA - 2025/03/31
PB - Mendeleev Communications
SP - 341-343
IS - 3
VL - 35
ER -
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@article{2025_Filatov,
author = {Vadim Evgenievich Filatov and Dmitrii Aleksandrovich Iuzabchuk and Dmitry Alexandrovich Guk and Dmitrii Anatol'evich Lemenovskii and Elena Kimovna Beloglazkina},
title = {Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7646},
number = {3},
pages = {341--343},
doi = {10.71267/mencom.7646}
}
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Filatov, Vadim Evgenievich, et al. “Facile, efficient and green phthalimide synthesis in supercritical carbon dioxide.” Mendeleev Communications, vol. 35, no. 3, Mar. 2025, pp. 341-343. https://mendcomm.colab.ws/publications/10.71267/mencom.7646.

Keywords

amines.
green synthesis
phthalic ahhydride
phthalimides
supercritical carbon dioxide

Abstract

The reactions between phthalic anhydrides and primary amines in supercritical CO2 (80-110 bar) to afford the corresponding phthalimides proceed at temperatures of 120-130 °C (aliphatic amines) or 260-275 °C (aromatic amines). The developed procedure fully complies with the principles of green chemistry and allows one to obtain target phthalimides in 65-85% isolated yields, without additional purification and extraction.

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