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Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock

Ksenia Borisovna Tereshkina 1
Ksenia Borisovna Tereshkina
, 
Victoriya Vyacheslavovna Potokina 2
Victoriya Vyacheslavovna Potokina
, 
Eduard Vladimirovich Tereshkin 1
Eduard Vladimirovich Tereshkin
, 
Vladislav V Kovalenko 1
Vladislav V Kovalenko
, 
Yurii Fedorovich Krupyanskii 1
Yurii Fedorovich Krupyanskii
, 
Nataliya G Loiko 2
Nataliya G Loiko
1 N. N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2 Federal Research Centre ‘Fundamentals of Biotechnology’ of the Russian Academy of Sciences, 119071 Moscow, Russian Federation
10.71267/mencom.7596
Published 2025-02-18
Communication , Volume 35, Issue 2, 139-141
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Tereshkina K. B. et al. Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock // Mendeleev Communications. 2025. Vol. 35. No. 2. pp. 139-141.
GOST all authors (up to 50) Copy
Tereshkina K. B., Potokina V. V., Tereshkin E. V., Kovalenko V. V., Krupyanskii Y. F., Loiko N. G. Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock // Mendeleev Communications. 2025. Vol. 35. No. 2. pp. 139-141.
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TY - JOUR
DO - 10.71267/mencom.7596
UR - https://mendcomm.colab.ws/publications/10.71267/mencom.7596
TI - Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock
T2 - Mendeleev Communications
AU - Tereshkina, Ksenia Borisovna
AU - Potokina, Victoriya Vyacheslavovna
AU - Tereshkin, Eduard Vladimirovich
AU - Kovalenko, Vladislav V
AU - Krupyanskii, Yurii Fedorovich
AU - Loiko, Nataliya G
PY - 2025
DA - 2025/02/18
PB - Mendeleev Communications
SP - 139-141
IS - 2
VL - 35
ER -
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@article{2025_Tereshkina,
author = {Ksenia Borisovna Tereshkina and Victoriya Vyacheslavovna Potokina and Eduard Vladimirovich Tereshkin and Vladislav V Kovalenko and Yurii Fedorovich Krupyanskii and Nataliya G Loiko},
title = {Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock},
journal = {Mendeleev Communications},
year = {2025},
volume = {35},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.71267/mencom.7596},
number = {2},
pages = {139--141},
doi = {10.71267/mencom.7596}
}
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Tereshkina, Ksenia Borisovna, et al. “Protection mechanism of Dps protein of bacterial DNA during sublethal heat shock.” Mendeleev Communications, vol. 35, no. 2, Feb. 2025, pp. 139-141. https://mendcomm.colab.ws/publications/10.71267/mencom.7596.

Keywords

DNA-binding protein Dps
Escherichia coli
heat shock
mechanism of protective action.
molecular modulation methods
stress tolerance

Abstract

The mechanism of protective action of the DNA-binding protein Dps from Escherichia coli during sublethal exposure to thermal shock has been deciphered using in vivo experimental methods and in silico molecular modelling methods. The strength of the DNA-Dps complex was shown to increase when the temperature was raised to 55 °C, and to maintain this state after cooling down to 28 °C. It is proved that this favors the survival of bacteria and their acquisition of additional stress resistance.

Funders

Russian Science Foundation
23-24-00250

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