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Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles

Dmitry Nikolaevich Kozhevnikov 1
Dmitry Nikolaevich Kozhevnikov
, 
Natalia Nikolaevna Kataeva 1
Natalia Nikolaevna Kataeva
, 
Vladimir Leonidovich Rusinov 1
Vladimir Leonidovich Rusinov
, 
Oleg Nikolaevich Chupakhin 1
Oleg Nikolaevich Chupakhin
, 
Grigorii Grigor'evich Alexandrov 2
Grigorii Grigor'evich Alexandrov
10.1070/MC2005v015n01ABEH001987
Published 2005-02-09
Communication , Volume 15, Issue 1, 31-33
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Kozhevnikov D. N. et al. Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles // Mendeleev Communications. 2005. Vol. 15. No. 1. pp. 31-33.
GOST all authors (up to 50) Copy
Kozhevnikov D. N., Kataeva N. N., Rusinov V. L., Chupakhin O. N., Alexandrov G. G. Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles // Mendeleev Communications. 2005. Vol. 15. No. 1. pp. 31-33.
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TY - JOUR
DO - 10.1070/MC2005v015n01ABEH001987
UR - https://mendcomm.colab.ws/publications/10.1070/MC2005v015n01ABEH001987
TI - Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles
T2 - Mendeleev Communications
AU - Kozhevnikov, Dmitry Nikolaevich
AU - Kataeva, Natalia Nikolaevna
AU - Rusinov, Vladimir Leonidovich
AU - Chupakhin, Oleg Nikolaevich
AU - Alexandrov, Grigorii Grigor'evich
PY - 2005
DA - 2005/02/09
PB - Mendeleev Communications
SP - 31-33
IS - 1
VL - 15
ER -
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@article{2005_Kozhevnikov,
author = {Dmitry Nikolaevich Kozhevnikov and Natalia Nikolaevna Kataeva and Vladimir Leonidovich Rusinov and Oleg Nikolaevich Chupakhin and Grigorii Grigor'evich Alexandrov},
title = {Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles},
journal = {Mendeleev Communications},
year = {2005},
volume = {15},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1070/MC2005v015n01ABEH001987},
number = {1},
pages = {31--33},
doi = {10.1070/MC2005v015n01ABEH001987}
}
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Kozhevnikov, Dmitry Nikolaevich, et al. “Transformations of 1,2,4-triazine 4-oxides to pyridazines and triazolo[4,3-b]pyridazines by the action of substituted acetonitriles.” Mendeleev Communications, vol. 15, no. 1, Feb. 2005, pp. 31-33. https://mendcomm.colab.ws/publications/10.1070/MC2005v015n01ABEH001987.

Abstract

Two types of ring transformations of 1,2,4-triazine to pyridazine were found: 1,2,4-triazine 4-oxides bearing ortho-halophenyl in the 3-position react with phenylacetonitrile under basic conditions to form 3-(2-oxyphenyl)[1,2,4]triazolo[4,3-b]pyridazines, while the reactions of 3,6-diaryl-1,2,4-triazin 4-oxides with sodium ethyl cyanoacetate afforded 2-aminopyridazines.

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