Home / Publications / Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure

Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure

Alexander Alexandrovich Bredikhin 1
Alexander Alexandrovich Bredikhin
, 
Zemfira Azal'evna Bredikhina 1
Zemfira Azal'evna Bredikhina
, 
Aidar Timergalievich Gubaidullin 1
Aidar Timergalievich Gubaidullin
, 
Dmitry Borisovich Krivolapov 1
Dmitry Borisovich Krivolapov
, 
Igor Anatol'evich Litvinov 1
Igor Anatol'evich Litvinov
10.1070/MC2004v014n06ABEH002037
Published 2004-12-17
Communication , Volume 14, Issue 6, 268-270
12
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Bredikhin A. A. et al. Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure // Mendeleev Communications. 2004. Vol. 14. No. 6. pp. 268-270.
GOST all authors (up to 50) Copy
Bredikhin A. A., Bredikhina Z. A., Gubaidullin A. T., Krivolapov D. B., Litvinov I. A. Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure // Mendeleev Communications. 2004. Vol. 14. No. 6. pp. 268-270.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1070/MC2004v014n06ABEH002037
UR - https://mendcomm.colab.ws/publications/10.1070/MC2004v014n06ABEH002037
TI - Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure
T2 - Mendeleev Communications
AU - Bredikhin, Alexander Alexandrovich
AU - Bredikhina, Zemfira Azal'evna
AU - Gubaidullin, Aidar Timergalievich
AU - Krivolapov, Dmitry Borisovich
AU - Litvinov, Igor Anatol'evich
PY - 2004
DA - 2004/12/17
PB - Mendeleev Communications
SP - 268-270
IS - 6
VL - 14
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2004_Bredikhin,
author = {Alexander Alexandrovich Bredikhin and Zemfira Azal'evna Bredikhina and Aidar Timergalievich Gubaidullin and Dmitry Borisovich Krivolapov and Igor Anatol'evich Litvinov},
title = {Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure},
journal = {Mendeleev Communications},
year = {2004},
volume = {14},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1070/MC2004v014n06ABEH002037},
number = {6},
pages = {268--270},
doi = {10.1070/MC2004v014n06ABEH002037}
}
MLA
Cite this
MLA Copy
Bredikhin, Alexander Alexandrovich, et al. “Rational approach to a conglomerate-forming propranolol derivative: pointed modifications of the crystal structure.” Mendeleev Communications, vol. 14, no. 6, Dec. 2004, pp. 268-270. https://mendcomm.colab.ws/publications/10.1070/MC2004v014n06ABEH002037.

Abstract

The crystal structure of racemic propranolol hydrochloride was reinvestigated and the main supramolecular solid-state motif (infinite homochiral chains) was found. Changes in the size of the central anion are accompanied by substantial differences in crystal packing leading to a homochiral crystal lattice of racemic conglomerate.

References

1.
Stereoisomerism and drug action
Lehmann P.A.
Trends in Pharmacological Sciences, 1986
2.
10.1070/MC2004v014n06ABEH002037_bib1_2
Drug Stereochemistry: Analytical Methods, Pharmacology, 1993
3.
10.1070/MC2004v014n06ABEH002037_bib1_3
Casy
The Steric Factor in Medicinal Chemistry, 1993
4.
10.1070/MC2004v014n06ABEH002037_bib1_4
Aboul-Enein
Impact of Stereochemistry on Drug Development and Use, 1997
5.
CHIRAL DRUGS
STINSON S.C.
Chemical & Engineering News, 1993
6.
Optical resolution by direct crystallization of enantiomer mixtures
Collet A., Brienne M.J., Jacques J.
Chemical Reviews, 1980
7.
10.1070/MC2004v014n06ABEH002037_bib4
Jaques
Enantiomers, Racemates, and Resolutions, 1994
8.
The Merck Index, 12th edn., ed. S. Budavari, Merck and Co., Inc., Whitehouse Station, 1996, p. 8025.
9.
Optical Isomers of Propranolol
HOWE R., SHANKS R.G.
Nature, 1966
12.
Stereoselective Vascular Effects of the (R)- and (S)-Enantiomers of Propranolol and Atenolol
Stoschitzky K., Lindner W., Kiowski W.
Journal of Cardiovascular Pharmacology, 2006
13.
Melting point phase diagrams of free base and hydrochloride salts of bevantolol, pindolol and propranolol
Neau S.H., Shinwari M.K., Hellmuth E.W.
International Journal of Pharmaceutics, 1993
14.
10.1070/MC2004v014n06ABEH002037_bib9
Bredikhin
Izv. Akad. Nauk, Ser. Khim., 2003
15.
Conformations cristallines d'adrénolytiques β-bloquants: propranolol et alprénolol
Barrans Y., Cotrait M., Dangoumau J.
Acta Crystallographica Section B, 1973
16.
The crystal structures of dichloroisoproterenol, propranolol and propranolol hydrochloride
Ammon H.L., Howe D.-., Erhardt W.D., Balsamo A., Macchia B., Macchia F., Keefe W.E.
Acta Crystallographica Section B, 1977
17.
E-map improvement in direct procedures
Altomare A., Cascarano G., Giacovazzo C., Viterbo D.
Acta Crystallographica Section A Foundations of Crystallography, 1991
18.
10.1070/MC2004v014n06ABEH002037_bib13
Straver
MolEN Structure Determination System, Nonius B. V., 1994
21.
10.1070/MC2004v014n06ABEH002037_bib15
Bredikhin
Izv. Akad. Nauk, Ser. Khim., 1998