Home / Publications / Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form

Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form

Galina Valentinovna Pazynina 1
Galina Valentinovna Pazynina
, 
Tatiana Victorovna Tyrtysh 1
Tatiana Victorovna Tyrtysh
, 
10.1070/MC2002v012n04ABEH001591
Published 2002-09-12
Communication , Volume 12, Issue 4, 143-145
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Pazynina G. V., Tyrtysh T. V., Bovin N. V. Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form // Mendeleev Communications. 2002. Vol. 12. No. 4. pp. 143-145.
GOST all authors (up to 50) Copy
Pazynina G. V., Tyrtysh T. V., Bovin N. V. Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form // Mendeleev Communications. 2002. Vol. 12. No. 4. pp. 143-145.
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TY - JOUR
DO - 10.1070/MC2002v012n04ABEH001591
UR - https://mendcomm.colab.ws/publications/10.1070/MC2002v012n04ABEH001591
TI - Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form
T2 - Mendeleev Communications
AU - Pazynina, Galina Valentinovna
AU - Tyrtysh, Tatiana Victorovna
AU - Bovin, Nicolai Vladimirovich
PY - 2002
DA - 2002/09/12
PB - Mendeleev Communications
SP - 143-145
IS - 4
VL - 12
ER -
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@article{2002_Pazynina,
author = {Galina Valentinovna Pazynina and Tatiana Victorovna Tyrtysh and Nicolai Vladimirovich Bovin},
title = {Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form},
journal = {Mendeleev Communications},
year = {2002},
volume = {12},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1070/MC2002v012n04ABEH001591},
number = {4},
pages = {143--145},
doi = {10.1070/MC2002v012n04ABEH001591}
}
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Pazynina, Galina Valentinovna, et al. “Synthesis of histo blood-group antigens A and B (type 2), xenoantigen Galα1-3Galβ1-4GlcNAc and related type 2 backbone oligosaccharides as haptens in spacered form.” Mendeleev Communications, vol. 12, no. 4, Sep. 2002, pp. 143-145. https://mendcomm.colab.ws/publications/10.1070/MC2002v012n04ABEH001591.

Abstract

The partial α-fucosylation of spacered (sp = CH2CH2CH2NH2) N-acetyl β-lactosamine derivative having free hydroxy groups at C-3 and C-2′ gives rise to oligosaccharides H (type 2), Lex and Ley, the first one was further elongated giving rise to A (type 2) or B (type 2) tetrasaccharides; spacered trisaccharides Galα1-3Galβ1-4GlcNAc and Galα1-4Galβ1-4GlcNAc were synthesised by the partial α-galactosylation of N-acetyl β-lactosamine derivative, having free hydroxy groups at C-4′ and C-3′.

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