Home / Publications / Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring

Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring

Evgeniy V Blyumin 1
Evgeniy V Blyumin
, 
Yulian Mikhailovich Volovenko 1
Yulian Mikhailovich Volovenko
1 Department of Chemistry, T.G. Shevchenko Kiev National University, Kiev, Ukraine
10.1070/MC2000v010n06ABEH001313
Published 2000-12-07
Communication , Volume 10, Issue 6, 237-238
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Blyumin E. V., Volovenko Y. M. Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring // Mendeleev Communications. 2000. Vol. 10. No. 6. pp. 237-238.
GOST all authors (up to 50) Copy
Blyumin E. V., Volovenko Y. M. Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring // Mendeleev Communications. 2000. Vol. 10. No. 6. pp. 237-238.
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TY - JOUR
DO - 10.1070/MC2000v010n06ABEH001313
UR - https://mendcomm.colab.ws/publications/10.1070/MC2000v010n06ABEH001313
TI - Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring
T2 - Mendeleev Communications
AU - Blyumin, Evgeniy V
AU - Volovenko, Yulian Mikhailovich
PY - 2000
DA - 2000/12/07
PB - Mendeleev Communications
SP - 237-238
IS - 6
VL - 10
ER -
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@article{2000_Blyumin,
author = {Evgeniy V Blyumin and Yulian Mikhailovich Volovenko},
title = {Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring},
journal = {Mendeleev Communications},
year = {2000},
volume = {10},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1070/MC2000v010n06ABEH001313},
number = {6},
pages = {237--238},
doi = {10.1070/MC2000v010n06ABEH001313}
}
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Blyumin, Evgeniy V., and Yulian Mikhailovich Volovenko. “Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid and its esters with amines. The inverse of reactivity in a pyrimidine ring.” Mendeleev Communications, vol. 10, no. 6, Dec. 2000, pp. 237-238. https://mendcomm.colab.ws/publications/10.1070/MC2000v010n06ABEH001313.

Abstract

Reactions of 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid with aliphatic amines afford 2-amino-5-chloro-4-pyrimidinecarboxylic acid, whereas 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylates form 5-amino-2-methylsulfonyl-4-pyrimidinecarboxylates under the same conditions.

References

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The Pyrimidines. Supplement II, 1985
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