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Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms

Vyacheslav Yakovlevich Sosnovskikh 1
Vyacheslav Yakovlevich Sosnovskikh
, 
Ivan Ivanovich Vorontsov 2
Ivan Ivanovich Vorontsov
, 
Valentin Alekseevich Kutsenko 1
Valentin Alekseevich Kutsenko
, 
Yurii Grigorjevich Yatluk 1
Yurii Grigorjevich Yatluk
10.1070/MC2000v010n02ABEH001209
Published 2000-03-30
Communication , Volume 10, Issue 2, 56-58
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Sosnovskikh V. Y. et al. Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms // Mendeleev Communications. 2000. Vol. 10. No. 2. pp. 56-58.
GOST all authors (up to 50) Copy
Sosnovskikh V. Y., Vorontsov I. I., Kutsenko V. A., Yatluk Y. G. Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms // Mendeleev Communications. 2000. Vol. 10. No. 2. pp. 56-58.
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TY - JOUR
DO - 10.1070/MC2000v010n02ABEH001209
UR - https://mendcomm.colab.ws/publications/10.1070/MC2000v010n02ABEH001209
TI - Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms
T2 - Mendeleev Communications
AU - Sosnovskikh, Vyacheslav Yakovlevich
AU - Vorontsov, Ivan Ivanovich
AU - Kutsenko, Valentin Alekseevich
AU - Yatluk, Yurii Grigorjevich
PY - 2000
DA - 2000/03/30
PB - Mendeleev Communications
SP - 56-58
IS - 2
VL - 10
ER -
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@article{2000_Sosnovskikh,
author = {Vyacheslav Yakovlevich Sosnovskikh and Ivan Ivanovich Vorontsov and Valentin Alekseevich Kutsenko and Yurii Grigorjevich Yatluk},
title = {Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms},
journal = {Mendeleev Communications},
year = {2000},
volume = {10},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1070/MC2000v010n02ABEH001209},
number = {2},
pages = {56--58},
doi = {10.1070/MC2000v010n02ABEH001209}
}
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Sosnovskikh, Vyacheslav Yakovlevich, et al. “Unexpected isomerization in the series of fluorine-containing 2,3-dihydro-1H-1,4-diazepines with a 2-aminoethyl group at one of the nitrogen atoms.” Mendeleev Communications, vol. 10, no. 2, Mar. 2000, pp. 56-58. https://mendcomm.colab.ws/publications/10.1070/MC2000v010n02ABEH001209.

Abstract

Under kinetic control conditions, 6-methoxy-2-(1,1,2,2-tetrafluoroethyl)chromone reacts with diethylenetriamine to form 5-(2-hydroxy-5-methoxyphenyl)-7-(1,1,2,2-tetrafluoroethyl)-1,4,8-triazabicyclo[5.3.0]dec-4-ene, and the latter undergoes isomerization to the title compound, which is more thermodynamically stable.

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