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Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone

Olga Vladimirovna Gulyakevich 1
Olga Vladimirovna Gulyakevich
, 
Irene Leonovna Rubinova 1
Irene Leonovna Rubinova
, 
Dmitry Bronislavovich Rubinov 1
Dmitry Bronislavovich Rubinov
, 
Alexander Leonidovich Mikhal'chuk 1
Alexander Leonidovich Mikhal'chuk
10.1070/MC1998v008n05ABEH000954
Published 1998-09-10
Communication , Volume 8, Issue 5, 183-184
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Gulyakevich O. V. et al. Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone // Mendeleev Communications. 1998. Vol. 8. No. 5. pp. 183-184.
GOST all authors (up to 50) Copy
Gulyakevich O. V., Rubinova I. L., Rubinov D. B., Mikhal'chuk A. L. Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone // Mendeleev Communications. 1998. Vol. 8. No. 5. pp. 183-184.
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TY - JOUR
DO - 10.1070/MC1998v008n05ABEH000954
UR - https://mendcomm.colab.ws/publications/10.1070/MC1998v008n05ABEH000954
TI - Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone
T2 - Mendeleev Communications
AU - Gulyakevich, Olga Vladimirovna
AU - Rubinova, Irene Leonovna
AU - Rubinov, Dmitry Bronislavovich
AU - Mikhal'chuk, Alexander Leonidovich
PY - 1998
DA - 1998/09/10
PB - Mendeleev Communications
SP - 183-184
IS - 5
VL - 8
ER -
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@article{1998_Gulyakevich,
author = {Olga Vladimirovna Gulyakevich and Irene Leonovna Rubinova and Dmitry Bronislavovich Rubinov and Alexander Leonidovich Mikhal'chuk},
title = {Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone},
journal = {Mendeleev Communications},
year = {1998},
volume = {8},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1070/MC1998v008n05ABEH000954},
number = {5},
pages = {183--184},
doi = {10.1070/MC1998v008n05ABEH000954}
}
MLA
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Gulyakevich, Olga Vladimirovna, et al. “Direct synthesis of 17a-ethoxyimino-8-aza-D-homogonanes by annelation of 3,4-dihydroisoquinolines with 2-acetyl-5,5-dimethyl-3-ethoxyiminocyclohexanone.” Mendeleev Communications, vol. 8, no. 5, Sep. 1998, pp. 183-184. https://mendcomm.colab.ws/publications/10.1070/MC1998v008n05ABEH000954.

Abstract

The annelation reaction of Schiff bases by β,β’-tricarbonyl compounds has been extended to 3-ethoxyimino derivatives of 2-acylcyclohexane-1,3-diones. The first direct synthesis of 8-aza-D-homogonanes with a modified carbonyl group at the pharmacologically significant C(17a) position has been carried out.

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