Home / Publications / Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure

Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure

Vladimir Alexandrovich Glushkov 1
Vladimir Alexandrovich Glushkov
, 
Yurii Vladimirovich Shklyaev 1
Yurii Vladimirovich Shklyaev
10.1070/MC1998v008n01ABEH000881
Published 1998-02-28
Communication , Volume 8, Issue 1, 17-18
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Glushkov V. A., Shklyaev Y. V. Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure // Mendeleev Communications. 1998. Vol. 8. No. 1. pp. 17-18.
GOST all authors (up to 50) Copy
Glushkov V. A., Shklyaev Y. V. Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure // Mendeleev Communications. 1998. Vol. 8. No. 1. pp. 17-18.
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TY - JOUR
DO - 10.1070/MC1998v008n01ABEH000881
UR - https://mendcomm.colab.ws/publications/10.1070/MC1998v008n01ABEH000881
TI - Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure
T2 - Mendeleev Communications
AU - Glushkov, Vladimir Alexandrovich
AU - Shklyaev, Yurii Vladimirovich
PY - 1998
DA - 1998/02/28
PB - Mendeleev Communications
SP - 17-18
IS - 1
VL - 8
ER -
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@article{1998_Glushkov,
author = {Vladimir Alexandrovich Glushkov and Yurii Vladimirovich Shklyaev},
title = {Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure},
journal = {Mendeleev Communications},
year = {1998},
volume = {8},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1070/MC1998v008n01ABEH000881},
number = {1},
pages = {17--18},
doi = {10.1070/MC1998v008n01ABEH000881}
}
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Glushkov, Vladimir Alexandrovich, and Yurii Vladimirovich Shklyaev. “Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure.” Mendeleev Communications, vol. 8, no. 1, Feb. 1998, pp. 17-18. https://mendcomm.colab.ws/publications/10.1070/MC1998v008n01ABEH000881.

Abstract

Treatment of 1,2- (or 1,4)-dimethoxybenzene with isobutylene oxide and an appropriate nitrile RCN in concentrated sulfuric acid leads to 1-R-6,7-(or 5,8-)dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolines.

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