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Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side

Vladimir Vadimovich Rozhkov 1
Vladimir Vadimovich Rozhkov
, 
Kirill Nikolaevich Makarov 2
Kirill Nikolaevich Makarov
, 
Sergey Nikolaevich Osipov 2
Sergey Nikolaevich Osipov
, 
Ivan Ivanovich Chervin 1
Ivan Ivanovich Chervin
, 
Anatolii Victorovich Ignatenko 3
Anatolii Victorovich Ignatenko
, 
Remir Grigorevich Kostyanovsky 1
Remir Grigorevich Kostyanovsky
10.1070/MC1997v007n06ABEH000831
Published 1997-12-31
Communication , Volume 7, Issue 6, 229-230
3
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Rozhkov V. V. et al. Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side // Mendeleev Communications. 1997. Vol. 7. No. 6. pp. 229-230.
GOST all authors (up to 50) Copy
Rozhkov V. V., Makarov K. N., Osipov S. N., Chervin I. I., Ignatenko A. V., Kostyanovsky R. G. Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side // Mendeleev Communications. 1997. Vol. 7. No. 6. pp. 229-230.
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TY - JOUR
DO - 10.1070/MC1997v007n06ABEH000831
UR - https://mendcomm.colab.ws/publications/10.1070/MC1997v007n06ABEH000831
TI - Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side
T2 - Mendeleev Communications
AU - Rozhkov, Vladimir Vadimovich
AU - Makarov, Kirill Nikolaevich
AU - Osipov, Sergey Nikolaevich
AU - Chervin, Ivan Ivanovich
AU - Ignatenko, Anatolii Victorovich
AU - Kostyanovsky, Remir Grigorevich
PY - 1997
DA - 1997/12/31
PB - Mendeleev Communications
SP - 229-230
IS - 6
VL - 7
ER -
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@article{1997_Rozhkov,
author = {Vladimir Vadimovich Rozhkov and Kirill Nikolaevich Makarov and Sergey Nikolaevich Osipov and Ivan Ivanovich Chervin and Anatolii Victorovich Ignatenko and Remir Grigorevich Kostyanovsky},
title = {Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side},
journal = {Mendeleev Communications},
year = {1997},
volume = {7},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1070/MC1997v007n06ABEH000831},
number = {6},
pages = {229--230},
doi = {10.1070/MC1997v007n06ABEH000831}
}
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Rozhkov, Vladimir Vadimovich, et al. “Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side.” Mendeleev Communications, vol. 7, no. 6, Dec. 1997, pp. 229-230. https://mendcomm.colab.ws/publications/10.1070/MC1997v007n06ABEH000831.

Abstract

N-Fluorination and N-chlorination of methyl 2-trifluoromethylaziridine-2-carboxylate occurs predominantly from the more hindered side owing to the fixed orientation of the lone electron pair of the N atom caused by the formation of an intramolecular H-bond.

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