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Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines

Electron Aleksandrovich Mistryukov 1
Electron Aleksandrovich Mistryukov
Olga N Sorokina 1
Olga N Sorokina
Alexander Èlektronovich Mistryukov 2
Alexander Èlektronovich Mistryukov
Published 1996-12-31
CommunicationVolume 6, Issue 6, 39-241
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Mistryukov E. A., Sorokina O. N., Mistryukov A. È. Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines // Mendeleev Communications. 1996. Vol. 6. No. 6. pp. 39-241.
GOST all authors (up to 50) Copy
Mistryukov E. A., Sorokina O. N., Mistryukov A. È. Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines // Mendeleev Communications. 1996. Vol. 6. No. 6. pp. 39-241.
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TY - JOUR
DO - 10.1070/MC1996v006n06ABEH000741
UR - https://mendcomm.colab.ws/publications/10.1070/MC1996v006n06ABEH000741
TI - Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines
T2 - Mendeleev Communications
AU - Mistryukov, Electron Aleksandrovich
AU - Sorokina, Olga N
AU - Mistryukov, Alexander Èlektronovich
PY - 1996
DA - 1996/12/31
PB - Mendeleev Communications
SP - 39-241
IS - 6
VL - 6
ER -
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@article{1996_Mistryukov,
author = {Electron Aleksandrovich Mistryukov and Olga N Sorokina and Alexander Èlektronovich Mistryukov},
title = {Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines},
journal = {Mendeleev Communications},
year = {1996},
volume = {6},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1070/MC1996v006n06ABEH000741},
number = {6},
pages = {39--241},
doi = {10.1070/MC1996v006n06ABEH000741}
}
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Mistryukov, Electron Aleksandrovich, et al. “Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines.” Mendeleev Communications, vol. 6, no. 6, Dec. 1996, pp. 39-241. https://mendcomm.colab.ws/publications/10.1070/MC1996v006n06ABEH000741.

Abstract

The efficient Lewis acid assisted cyclisation of β-phenylethylamide into dihydroisoquinolines was optimised in relation to metal chloride catalyst, and by X-ray crystallography a new type of non-bonded interaction in the cyclic systems was demonstrated: face coordination of the Cl-anion and an electron deficient pyridinium π-system.