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Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids

Alevtina Mikhailovna Turuta 1
Alevtina Mikhailovna Turuta
, 
Alexey Vladimirovich Kamernitskii 1
Alexey Vladimirovich Kamernitskii
, 
Natalia Evgen'evna Voishvillo 1
Natalia Evgen'evna Voishvillo
, 
Nino Vasil'evna Jlantiashvili 1
Nino Vasil'evna Jlantiashvili
, 
Aleksandr P Krymov 2
Aleksandr P Krymov
, 
Nicolai V Domrachev 2
Nicolai V Domrachev
2 All-Russia Scientific Centre of Biologically Active Compounds, Moscow region, Russian Federation
10.1070/MC1991v001n03ABEH000069
Published 1991-09-30
Communication , Volume 1, Issue 3, 113-114
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Turuta A. M. et al. Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids // Mendeleev Communications. 1991. Vol. 1. No. 3. pp. 113-114.
GOST all authors (up to 50) Copy
Turuta A. M., Kamernitskii A. V., Voishvillo N. E., Jlantiashvili N. V., Krymov A. P., Domrachev N. V. Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids // Mendeleev Communications. 1991. Vol. 1. No. 3. pp. 113-114.
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TY - JOUR
DO - 10.1070/MC1991v001n03ABEH000069
UR - https://mendcomm.colab.ws/publications/10.1070/MC1991v001n03ABEH000069
TI - Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids
T2 - Mendeleev Communications
AU - Turuta, Alevtina Mikhailovna
AU - Kamernitskii, Alexey Vladimirovich
AU - Voishvillo, Natalia Evgen'evna
AU - Jlantiashvili, Nino Vasil'evna
AU - Krymov, Aleksandr P
AU - Domrachev, Nicolai V
PY - 1991
DA - 1991/09/30
PB - Mendeleev Communications
SP - 113-114
IS - 3
VL - 1
ER -
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@article{1991_Turuta,
author = {Alevtina Mikhailovna Turuta and Alexey Vladimirovich Kamernitskii and Natalia Evgen'evna Voishvillo and Nino Vasil'evna Jlantiashvili and Aleksandr P Krymov and Nicolai V Domrachev},
title = {Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids},
journal = {Mendeleev Communications},
year = {1991},
volume = {1},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1070/MC1991v001n03ABEH000069},
number = {3},
pages = {113--114},
doi = {10.1070/MC1991v001n03ABEH000069}
}
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Turuta, Alevtina Mikhailovna, et al. “Use of 20,20-Dimethylacetal Protection in Microbial Hydroxylation and Dehydrogenation of Steroids.” Mendeleev Communications, vol. 1, no. 3, Sep. 1991, pp. 113-114. https://mendcomm.colab.ws/publications/10.1070/MC1991v001n03ABEH000069.

Abstract

The 20,20-dimethylacetal group proposed for protection of the 20-oxo group in 21-hydroxylation of steroids by hypervalent iodine compounds has been successfully used to hamper side reactions in microbial 9α- and 11β-hydroxylation and 4-dehydrogenation of 21-hydroxy-16α,17α-epoxypregnanes by Rhodococcus sp., Curvularia lunata and Corynebacterium mediolanum cultures.

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