Keywords
drug delivery.
glycerolipids
imidazolium salts
liposomes
mesoporous silica nanoparticles
sol–gel synthesis
template
Abstract
A new method for encapsulating cationic glycerolipids is proposed, based on their use as templating agents in the sol-gel synthesis of mesoporous silica particles. Using the example of rac-N-{4-[(2-ethoxy-3-octadecyloxyprop-1-yl)-oxycarbonyl]butyl}-N’-methylimidazolium iodide, it is shown that this method results in the formation of high-capacity container particles with a pronounced porous structure and a narrow size distribution.
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