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Enthalpy and heat capacity of hydration of the cytostatic Dioxadet

Nataliya Leonidovna Smirnova 1
Nataliya Leonidovna Smirnova
Andrey Vladimirovich Kustov 1
Andrey Vladimirovich Kustov
Airat Al'bertovich Notfullin 2
Airat Al'bertovich Notfullin
Michail I Yagofarov 2
Michail I Yagofarov
Dmitriy Vyacheslavovich Batov 1
Dmitriy Vyacheslavovich Batov
Konstantin Nikolaevich Semenov 3
Konstantin Nikolaevich Semenov
1 G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russian Federation
2 Kazan Federal University, Kazan, Russian Federation
3 I.P. Pavlov First St. Petersburg State Medical University, St. Petersburg, Russian Federation
Published 2024-09-09
CommunicationVolume 34, Issue 5, 680-681
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Smirnova N. L. et al. Enthalpy and heat capacity of hydration of the cytostatic Dioxadet // Mendeleev Communications. 2024. Vol. 34. No. 5. pp. 680-681.
GOST all authors (up to 50) Copy
Smirnova N. L., Kustov A. V., Notfullin A. A., Yagofarov M. I., Batov D. V., Semenov K. N. Enthalpy and heat capacity of hydration of the cytostatic Dioxadet // Mendeleev Communications. 2024. Vol. 34. No. 5. pp. 680-681.
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TY - JOUR
DO - 10.1016/j.mencom.2024.09.017
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.09.017
TI - Enthalpy and heat capacity of hydration of the cytostatic Dioxadet
T2 - Mendeleev Communications
AU - Smirnova, Nataliya Leonidovna
AU - Kustov, Andrey Vladimirovich
AU - Notfullin, Airat Al'bertovich
AU - Yagofarov, Michail I
AU - Batov, Dmitriy Vyacheslavovich
AU - Semenov, Konstantin Nikolaevich
PY - 2024
DA - 2024/09/09
PB - Mendeleev Communications
SP - 680-681
IS - 5
VL - 34
ER -
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@article{2024_Smirnova,
author = {Nataliya Leonidovna Smirnova and Andrey Vladimirovich Kustov and Airat Al'bertovich Notfullin and Michail I Yagofarov and Dmitriy Vyacheslavovich Batov and Konstantin Nikolaevich Semenov},
title = {Enthalpy and heat capacity of hydration of the cytostatic Dioxadet},
journal = {Mendeleev Communications},
year = {2024},
volume = {34},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.09.017},
number = {5},
pages = {680--681},
doi = {10.1016/j.mencom.2024.09.017}
}
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Smirnova, Nataliya Leonidovna, et al. “Enthalpy and heat capacity of hydration of the cytostatic Dioxadet.” Mendeleev Communications, vol. 34, no. 5, Sep. 2024, pp. 680-681. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.09.017.

Keywords

Dioxadet
enthalpy
heat capacity.
hydration
solution
sublimation

Abstract

Thermochemical data on hydration of the well-established anticancer agent Dioxadet were obtained. Its enthalpies of solution and sublimation at various temperatures were determined calorimetrically, and on their basis the standard enthalpy (ΔhydrH0 = −154.6 ± 3.6 kJ mol−1) and the standard heat capacity (ΔhydrCp0 = 384 ± 80 J mol−1 K−1) of the transfer of the solute from the state of an ideal gas to an aqueous solution at infinite dilution at 298.15 K were calculated.

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