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Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids

Natalya Shamil'evna Lebedeva 1
Natalya Shamil'evna Lebedeva
Elena Sergeevna Yurina 1
Elena Sergeevna Yurina
Aleksey N Kiselev 2
Aleksey N Kiselev
Mikhail Aleksandrovich Lebedev 2
Mikhail Aleksandrovich Lebedev
Sergei Aleksandrovich Syrbu 1
Sergei Aleksandrovich Syrbu
1 G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russian Federation
2 Ivanovo State University of Chemistry and Technology, Ivanovo, Russian Federation
Published 2024-06-19
CommunicationVolume 34, Issue 4, 525-527
4
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Lebedeva N. S. et al. Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids // Mendeleev Communications. 2024. Vol. 34. No. 4. pp. 525-527.
GOST all authors (up to 50) Copy
Lebedeva N. S., Yurina E. S., Kiselev A. N., Lebedev M. A., Syrbu S. A. Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids // Mendeleev Communications. 2024. Vol. 34. No. 4. pp. 525-527.
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TY - JOUR
DO - 10.1016/j.mencom.2024.06.018
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.06.018
TI - Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids
T2 - Mendeleev Communications
AU - Lebedeva, Natalya Shamil'evna
AU - Yurina, Elena Sergeevna
AU - Kiselev, Aleksey N
AU - Lebedev, Mikhail Aleksandrovich
AU - Syrbu, Sergei Aleksandrovich
PY - 2024
DA - 2024/06/19
PB - Mendeleev Communications
SP - 525-527
IS - 4
VL - 34
ER -
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@article{2024_Lebedeva,
author = {Natalya Shamil'evna Lebedeva and Elena Sergeevna Yurina and Aleksey N Kiselev and Mikhail Aleksandrovich Lebedev and Sergei Aleksandrovich Syrbu},
title = {Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids},
journal = {Mendeleev Communications},
year = {2024},
volume = {34},
publisher = {Mendeleev Communications},
month = {Jun},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.06.018},
number = {4},
pages = {525--527},
doi = {10.1016/j.mencom.2024.06.018}
}
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Lebedeva, Natalya Shamil'evna, et al. “Unsymmetrical cationic porphyrin that forms sedimentation-unstable complexes with nucleic acids.” Mendeleev Communications, vol. 34, no. 4, Jun. 2024, pp. 525-527. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.06.018.

Keywords

cationic porphyrin
DNA
isolation of DNA.
nucleic acids
pyridinium compounds

Abstract

A water-soluble cationic porphyrin containing N-methyl- pyridinium fragments and an indole residue, namely, 5-[4-(1-methylindol-2-yl)phenyl]-10,15,20-tris(1-methyl- pyridinium-3-yl)porphyrin triiodide, has been synthesized. The porphyrin forms sedimentation unstable complexes with low and high molecular weight nucleic acids. This ability to precipitate nucleic acids can be used in laboratory, clinical and research practice for isolating nucleic acids.

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