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Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids

Anastasia Mikhailovna Zhirkova 1
Anastasia Mikhailovna Zhirkova
, 
Kirill Vladimirovich Zaitsev 1
Kirill Vladimirovich Zaitsev
, 
Andrey Anatol'evich Prishchenko 1
Andrey Anatol'evich Prishchenko
, 
Mikhail V. Vasiliev 1
Mikhail V. Vasiliev
, 
Marina Vyacheslavovna Kotova 1
Marina Vyacheslavovna Kotova
, 
Karina Alekseevich Uschakova 1
Karina Alekseevich Uschakova
, 
Laura Aregovna Martirosyan 1
Laura Aregovna Martirosyan
, 
1 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
10.1016/j.mencom.2024.04.029
Published 2024-04-22
Communication , Volume 34, Issue 3, 404-405
5
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Zhirkova A. M. et al. Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 404-405.
GOST all authors (up to 50) Copy
Zhirkova A. M., Zaitsev K. V., Prishchenko A. A., Vasiliev M. V., Kotova M. V., Uschakova K. A., Martirosyan L. A., Perminova I. V. Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 404-405.
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TY - JOUR
DO - 10.1016/j.mencom.2024.04.029
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.029
TI - Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids
T2 - Mendeleev Communications
AU - Zhirkova, Anastasia Mikhailovna
AU - Zaitsev, Kirill Vladimirovich
AU - Prishchenko, Andrey Anatol'evich
AU - Vasiliev, Mikhail V.
AU - Kotova, Marina Vyacheslavovna
AU - Uschakova, Karina Alekseevich
AU - Martirosyan, Laura Aregovna
AU - Perminova, Irina Vasil'evna
PY - 2024
DA - 2024/04/22
PB - Mendeleev Communications
SP - 404-405
IS - 3
VL - 34
ER -
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@article{2024_Zhirkova,
author = {Anastasia Mikhailovna Zhirkova and Kirill Vladimirovich Zaitsev and Andrey Anatol'evich Prishchenko and Mikhail V. Vasiliev and Marina Vyacheslavovna Kotova and Karina Alekseevich Uschakova and Laura Aregovna Martirosyan and Irina Vasil'evna Perminova},
title = {Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids},
journal = {Mendeleev Communications},
year = {2024},
volume = {34},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.029},
number = {3},
pages = {404--405},
doi = {10.1016/j.mencom.2024.04.029}
}
MLA
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MLA Copy
Zhirkova, Anastasia Mikhailovna, et al. “Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids.” Mendeleev Communications, vol. 34, no. 3, Apr. 2024, pp. 404-405. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.029.

Keywords

bis(phosphonic) acids
carboxylic acid chlorides
hexamethyldisilazane
NMR spectroscopy.
organophosphorus compounds
phosphorous acid
tris(trimethylsilyl) phosphite

Abstract

‘Technical’ tris(trimethylsilyl) phosphite, (Me3SiO)3P, as a mixture with (Me3SiO)2P(O)H and (Me3SiO)3P(O) (71 : 20 : 9) was obtained upon the action of (Me Si) NH on phosphorous acid H3PO3 in the presence of catalytic amount of Me3SiCl. The action of this material on acid chlorides RC(O)Cl affords (hydroxymethylene)bis(phosphonic) acids RC(OH)[P(O)(OH)2]2 in preparative yields.

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