Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data

Egorova, Ksenia Sergeevna; Posvyatenko, Alexandra Victorovna; Galushko, Alexey Sergeevich; Kolesnikov, Andrey Eduardovich

doi:10.1016/j.mencom.2024.04.013

Home / Publications / Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data

Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data

Ksenia Sergeevna Egorova ¹

Ksenia Sergeevna Egorova

0000-0002-1102-2868

,

Alexandra Victorovna Posvyatenko ^{1, 2}

Alexandra Victorovna Posvyatenko

,

Alexey Sergeevich Galushko ¹

Alexey Sergeevich Galushko

,

Andrey Eduardovich Kolesnikov ¹

Andrey Eduardovich Kolesnikov

¹ N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

² Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation

10.1016/j.mencom.2024.04.013

Copy DOI

Published 2024-04-22

Communication , Volume 34, Issue 3, 351-353

View PDF

Supporting information

Graphical abstract

0

Share

Cite this

GOST

|

Cite this

GOST Copy

Egorova K. S. et al. Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 351-353.

GOST all authors (up to 50) Copy

Egorova K. S., Posvyatenko A. V., Galushko A. S., Kolesnikov A. E. Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 351-353.

RIS

|

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.mencom.2024.04.013

UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.013

TI - Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data

T2 - Mendeleev Communications

AU - Egorova, Ksenia Sergeevna

AU - Posvyatenko, Alexandra Victorovna

AU - Galushko, Alexey Sergeevich

AU - Kolesnikov, Andrey Eduardovich

PY - 2024

DA - 2024/04/22

PB - Mendeleev Communications

SP - 351-353

IS - 3

VL - 34

ER -

BibTex

|

Cite this

BibTex (up to 50 authors) Copy

@article{2024_Egorova,

author = {Ksenia Sergeevna Egorova and Alexandra Victorovna Posvyatenko and Alexey Sergeevich Galushko and Andrey Eduardovich Kolesnikov},

title = {Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data},

journal = {Mendeleev Communications},

year = {2024},

volume = {34},

publisher = {Mendeleev Communications},

month = {Apr},

url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.013},

number = {3},

pages = {351--353},

doi = {10.1016/j.mencom.2024.04.013}

}

MLA

Cite this

MLA Copy

Egorova, Ksenia Sergeevna, et al. “Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data.” Mendeleev Communications, vol. 34, no. 3, Apr. 2024, pp. 351-353. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.013.

Keywords

11’-biphenyl

acute toxicity

bio-Profile

bio-Strip

C–C cross-coupling

cell culture

cytotoxicity

rat

toxicity potential.

Abstract

In this work, by means of bio-Strips and toxicity potentials, we compare the results of analysis of toxic potentials of chemical reactions when using cytotoxicity or acute toxicity data. Here, 24 routes of synthesis of 1,1’-biphenyl are used for exemplary purposes.