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A novel thermoresponsive polypeptide: synthesis and characterization

, 
Natalya N Zakharova 1
Natalya N Zakharova
, 
Elena Nikolaevna Vlasova 1
Elena Nikolaevna Vlasova
, 
Evgenia Georgievna Korzhikova-Vlakh 1
Evgenia Georgievna Korzhikova-Vlakh
1 Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russian Federation
10.1016/j.mencom.2024.04.012
Published 2024-04-22
Communication , Volume 34, Issue 3, 348-350
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Tarasenko I. I. et al. A novel thermoresponsive polypeptide: synthesis and characterization // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 348-350.
GOST all authors (up to 50) Copy
Tarasenko I. I., Zakharova N. N., Vlasova E. N., Korzhikova-Vlakh E. G. A novel thermoresponsive polypeptide: synthesis and characterization // Mendeleev Communications. 2024. Vol. 34. No. 3. pp. 348-350.
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TY - JOUR
DO - 10.1016/j.mencom.2024.04.012
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.012
TI - A novel thermoresponsive polypeptide: synthesis and characterization
T2 - Mendeleev Communications
AU - Tarasenko, Irina Il'inichna
AU - Zakharova, Natalya N
AU - Vlasova, Elena Nikolaevna
AU - Korzhikova-Vlakh, Evgenia Georgievna
PY - 2024
DA - 2024/04/22
PB - Mendeleev Communications
SP - 348-350
IS - 3
VL - 34
ER -
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@article{2024_Tarasenko,
author = {Irina Il'inichna Tarasenko and Natalya N Zakharova and Elena Nikolaevna Vlasova and Evgenia Georgievna Korzhikova-Vlakh},
title = {A novel thermoresponsive polypeptide: synthesis and characterization},
journal = {Mendeleev Communications},
year = {2024},
volume = {34},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.012},
number = {3},
pages = {348--350},
doi = {10.1016/j.mencom.2024.04.012}
}
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Tarasenko, Irina Il'inichna, et al. “A novel thermoresponsive polypeptide: synthesis and characterization.” Mendeleev Communications, vol. 34, no. 3, Apr. 2024, pp. 348-350. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.04.012.

Keywords

phase transition temperature.
poly(ψ-methyl glutamate)
poly(ψ-N-isopropyl glutamine)
polypeptide
thermoresponsive polymer

Abstract

Polypeptide consisting of ψ-N-isopropyl glutamine and glutamic acid (90 : 10, mol/mol) was synthesized by post- polymerization modification of poly(ψ-methyl glutamate). The obtained polypeptide exhibited thermoresponsive properties with the lowest critical solution temperature in the range of 41-54 °C depending on the medium and polymer concentration.

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