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An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide

Gulnaz F Sakhautdinova 1
Gulnaz F Sakhautdinova
, 
Ilshat Maratovich Sakhautdinov 1
Ilshat Maratovich Sakhautdinov
1 Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
10.1016/j.mencom.2024.02.036
Published 2024-02-19
Communication , Volume 34, Issue 2, 272-273
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Sakhautdinova G. F., Sakhautdinov I. M. An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide // Mendeleev Communications. 2024. Vol. 34. No. 2. pp. 272-273.
GOST all authors (up to 50) Copy
Sakhautdinova G. F., Sakhautdinov I. M. An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide // Mendeleev Communications. 2024. Vol. 34. No. 2. pp. 272-273.
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TY - JOUR
DO - 10.1016/j.mencom.2024.02.036
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.02.036
TI - An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide
T2 - Mendeleev Communications
AU - Sakhautdinova, Gulnaz F
AU - Sakhautdinov, Ilshat Maratovich
PY - 2024
DA - 2024/02/19
PB - Mendeleev Communications
SP - 272-273
IS - 2
VL - 34
ER -
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@article{2024_Sakhautdinova,
author = {Gulnaz F Sakhautdinova and Ilshat Maratovich Sakhautdinov},
title = {An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide},
journal = {Mendeleev Communications},
year = {2024},
volume = {34},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.02.036},
number = {2},
pages = {272--273},
doi = {10.1016/j.mencom.2024.02.036}
}
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Sakhautdinova, Gulnaz F., and Ilshat Maratovich Sakhautdinov. “An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide.” Mendeleev Communications, vol. 34, no. 2, Feb. 2024, pp. 272-273. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.02.036.

Keywords

1-a]iso-quinoline
alkaloids
homoveratrylamine
isoquinoline
N-(homoveratryl)maleimide
phosphorus ylide
Pictet–Spengler reaction.
tetrahydropyrrolo[2

Abstract

A simple and convenient synthesis of new isoquinolinone derivatives based on N-(homoveratryl)succinimide phosphorus ylide and natural aldehydes is suggested. The final formation of the tetrahydropyrrolo[2,1-a]isoquinoline framework occurs via the Pictet-Spengler cyclization.

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