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Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms

Darya Georgievna Sinelnikova 1
Darya Georgievna Sinelnikova
Olga Alexandrovna Novoskoltseva
Nataliya G Loiko 2
Nataliya G Loiko
Yuriy Alexandrovich Nikolaev 2
Yuriy Alexandrovich Nikolaev
Aleksandr Anatol'evich Yaroslavov 1
Aleksandr Anatol'evich Yaroslavov
1 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
2 Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow, Russian Federation
Published 2023-12-25
CommunicationVolume 34, Issue 1, 31-33
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Sinelnikova D. G. et al. Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms // Mendeleev Communications. 2023. Vol. 34. No. 1. pp. 31-33.
GOST all authors (up to 50) Copy
Sinelnikova D. G., Novoskoltseva O. A., Loiko N. G., Nikolaev Y. A., Yaroslavov A. A. Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms // Mendeleev Communications. 2023. Vol. 34. No. 1. pp. 31-33.
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TY - JOUR
DO - 10.1016/j.mencom.2024.01.010
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.01.010
TI - Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms
T2 - Mendeleev Communications
AU - Sinelnikova, Darya Georgievna
AU - Novoskoltseva, Olga Alexandrovna
AU - Loiko, Nataliya G
AU - Nikolaev, Yuriy Alexandrovich
AU - Yaroslavov, Aleksandr Anatol'evich
PY - 2023
DA - 2023/12/25
PB - Mendeleev Communications
SP - 31-33
IS - 1
VL - 34
ER -
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@article{2023_Sinelnikova,
author = {Darya Georgievna Sinelnikova and Olga Alexandrovna Novoskoltseva and Nataliya G Loiko and Yuriy Alexandrovich Nikolaev and Aleksandr Anatol'evich Yaroslavov},
title = {Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms},
journal = {Mendeleev Communications},
year = {2023},
volume = {34},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.01.010},
number = {1},
pages = {31--33},
doi = {10.1016/j.mencom.2024.01.010}
}
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Sinelnikova, Darya Georgievna, et al. “Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms.” Mendeleev Communications, vol. 34, no. 1, Dec. 2023, pp. 31-33. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2024.01.010.
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Keywords

alginate
antimicrobial activity.
microgels
negatively charged polycomplex
poly(diallyldimethylammonium chloride)

Abstract

Negatively charged polycomplexes have been prepared by electrostatic complexation of synthetic cationic poly(diallyldimethylammonium chloride) with excess anionic sodium alginate. These polycomplexes exhibit pronounced antimicrobial activity due to the biodegradation of the alginate matrix and the release of the biocidal polycation. The results obtained are promising for the development of simultaneously attractive and toxic polymer constructs capable of destroying microorganisms.

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