Keywords
alginate
antimicrobial activity.
microgels
negatively charged polycomplex
poly(diallyldimethylammonium chloride)
Abstract
Negatively charged polycomplexes have been prepared by electrostatic complexation of synthetic cationic poly(diallyldimethylammonium chloride) with excess anionic sodium alginate. These polycomplexes exhibit pronounced antimicrobial activity due to the biodegradation of the alginate matrix and the release of the biocidal polycation. The results obtained are promising for the development of simultaneously attractive and toxic polymer constructs capable of destroying microorganisms.
References
.
Gorshkova M.Y., Vanchugova L.V., Volkova I.F., Obydennova I.V., Valuev I.L., Valuev L.I.
Mendeleev Communications,
2022
.
Spiridonov V.V., Sadovnikov K.S., Vasilenko D.A., Sedenkova K.N., Lukmanova A.R., Markova A.A., Shibaeva A.V., Bolshakova A.V., Karlov S.S., Averina E.B., Yaroslavov A.A.
Mendeleev Communications,
2022
.
Kabanov V.A.
Russian Chemical Reviews,
2005
.
Izumrudov V.A.
Russian Chemical Reviews,
2008
.
Panova I.G., Shevaleva E.A., Gritskova I.A., Loiko N.G., Nikolaev Y.A., Novoskoltseva O.A., Yaroslavov A.A.
Polymers,
2022
.
Lee K.Y., Mooney D.J.
Progress in Polymer Science,
2012
.
Andrews J.M.
Journal of Antimicrobial Chemotherapy,
2001
.
de Melo Carrasco L., Sampaio J., Carmona-Ribeiro A.
International Journal of Molecular Sciences,
2015
.
Ishihara M., Kishimoto S., Nakamura S., Sato Y., Hattori H.
Polymers,
2019
.
Alfei S., Schito A.M.
Polymers,
2020
.
Cano-Vicent A., Hashimoto R., Takayama K., Serrano-Aroca Á.
Polymers,
2022
.
Liu Y., Nisisako T.
ACS Omega,
2020
.
Elbing K.L., Brent R.
Current Protocols in Molecular Biology,
2018
.
Novoskoltseva O.A., Loiko N.G., Nikolaev Y.A., Lisin A.O., Panova I.G., Yaroslavov A.A.
Polymer International,
2021
.
Qiu H., Si Z., Luo Y., Feng P., Wu X., Hou W., Zhu Y., Chan-Park M.B., Xu L., Huang D.
Frontiers in Bioengineering and Biotechnology,
2020
.
Zhang L., Li X., Zhang X., Li Y., Wang L.
Biotechnology for Biofuels,
2021
.
Thomas F., Barbeyron T., Tonon T., Génicot S., Czjzek M., Michel G.
Environmental Microbiology,
2012
.
Novoskoltseva O.A., Ryabaya O.O., Pozdniakova N.V., Yaroslavov A.A.
Colloids and Surfaces A: Physicochemical and Engineering Aspects,
2020
.
Exploring algae and cyanobacteria as a promising natural source of antiviral drug against SARS-CoV-2
Sami N., Ahmad R., Fatma T.
Biomedical Journal,
2021
.
Interpolyelectrolyte Complexes as an Emerging Technology for Pharmaceutical Delivery of Polypeptides
Fay J.M., Kabanov A.V.
Reviews and Advances in Chemistry,
2022
.
MURATA K., KAWAI S., HASHIMOTO W.
Proceedings of the Japan Academy Series B: Physical and Biological Sciences,
2022