Home / Publications / 3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine

3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine

Oleg Evgenevich Nasakin 1
Oleg Evgenevich Nasakin
, 
Elizaveta Sergeevna Ivanova 1
Elizaveta Sergeevna Ivanova
, 
Maxim Andreevich Maryasov 1
Maxim Andreevich Maryasov
, 
Vera Vladimirovna Andreeva 1
Vera Vladimirovna Andreeva
, 
Sergey Vladimirovich Karpov 1
Sergey Vladimirovich Karpov
, 
Olga Aleksandrovna Lodochnikova 2
Olga Aleksandrovna Lodochnikova
, 
Denis Yur'evich Grishaev 3
Denis Yur'evich Grishaev
1 Department of Chemistry, I.N. Ulyanov Chuvash State University, Cheboksary, Russian Federation
2 A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
3 Pharmacy Research & Education Center, Kazan Federal University, Kazan, Russian Federation
10.1016/j.mencom.2023.10.039
Published 2023-10-18
Communication , Volume 33, Issue 6, 856-857
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Nasakin O. E. et al. 3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine // Mendeleev Communications. 2023. Vol. 33. No. 6. pp. 856-857.
GOST all authors (up to 50) Copy
Nasakin O. E., Ivanova E. S., Maryasov M. A., Andreeva V. V., Karpov S. V., Lodochnikova O. A., Grishaev D. Y. 3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine // Mendeleev Communications. 2023. Vol. 33. No. 6. pp. 856-857.
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TY - JOUR
DO - 10.1016/j.mencom.2023.10.039
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.039
TI - 3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine
T2 - Mendeleev Communications
AU - Nasakin, Oleg Evgenevich
AU - Ivanova, Elizaveta Sergeevna
AU - Maryasov, Maxim Andreevich
AU - Andreeva, Vera Vladimirovna
AU - Karpov, Sergey Vladimirovich
AU - Lodochnikova, Olga Aleksandrovna
AU - Grishaev, Denis Yur'evich
PY - 2023
DA - 2023/10/18
PB - Mendeleev Communications
SP - 856-857
IS - 6
VL - 33
ER -
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@article{2023_Nasakin,
author = {Oleg Evgenevich Nasakin and Elizaveta Sergeevna Ivanova and Maxim Andreevich Maryasov and Vera Vladimirovna Andreeva and Sergey Vladimirovich Karpov and Olga Aleksandrovna Lodochnikova and Denis Yur'evich Grishaev},
title = {3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.039},
number = {6},
pages = {856--857},
doi = {10.1016/j.mencom.2023.10.039}
}
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Nasakin, Oleg Evgenevich, et al. “3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine.” Mendeleev Communications, vol. 33, no. 6, Oct. 2023, pp. 856-857. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.039.

Keywords

1
2-dihydro-3H-pyrrole-3
3
4
4-c]pyridine-3a
4-tetracyanoalkanones
4-tricarbonitriles
5-dihydro-1H-pyrrolo[3
7a-dicarbonitriles.
formaldehyde dimethylhydrazone
N
N-dimethylhydrazine
tetracyanoethylene
Thorpe–Ziegler type cyclization

Abstract

To utilize N,N-dimethylhydrazine, the corresponding +formaldehyde hydrazone was reacted with 1,1,2,2-tetra-cyanoethane or 3,3,4,4-tetracyanoalkanones. The first process yielded 5-amino-1-dimethylamino-1,2-dihydro-3H-pyrrole-3,3,4-tricarbonitrile while the second afforded pyrrolo[3,4-c]quinolone multifunctional derivatives. These resultant products hold promise in molecular design and pharmaceutical chemistry.

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