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L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction

Elizabeth A Dets 1
Elizabeth A Dets
,  , 
Irina Dmitrievna Grozdova 1
Irina Dmitrievna Grozdova
, 
Nikolay Sergeevich Melik-Nubarov 1
Nikolay Sergeevich Melik-Nubarov
1 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
10.1016/j.mencom.2023.10.018
Published 2023-10-18
Communication , Volume 33, Issue 6, 793-795
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Dets E. A. et al. L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction // Mendeleev Communications. 2023. Vol. 33. No. 6. pp. 793-795.
GOST all authors (up to 50) Copy
Dets E. A., Iakimov N. P., Grozdova I. D., Melik-Nubarov N. S. L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction // Mendeleev Communications. 2023. Vol. 33. No. 6. pp. 793-795.
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TY - JOUR
DO - 10.1016/j.mencom.2023.10.018
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.018
TI - L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction
T2 - Mendeleev Communications
AU - Dets, Elizabeth A
AU - Iakimov, Nikolai Petrovich
AU - Grozdova, Irina Dmitrievna
AU - Melik-Nubarov, Nikolay Sergeevich
PY - 2023
DA - 2023/10/18
PB - Mendeleev Communications
SP - 793-795
IS - 6
VL - 33
ER -
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@article{2023_Dets,
author = {Elizabeth A Dets and Nikolai Petrovich Iakimov and Irina Dmitrievna Grozdova and Nikolay Sergeevich Melik-Nubarov},
title = {L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.018},
number = {6},
pages = {793--795},
doi = {10.1016/j.mencom.2023.10.018}
}
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Dets, Elizabeth A., et al. “L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction.” Mendeleev Communications, vol. 33, no. 6, Oct. 2023, pp. 793-795. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.10.018.

Keywords

4
5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate
bis[2
chemo-induced PDT
L-tyrosine
micelles.
peroxyoxalate chemiluminescent reaction
poly-L-lactide–PEG amphiphilic copolymers

Abstract

We synthesized a biocompatible substrate of the peroxy-oxalate chemiluminescent reaction on the basis of N-benzoyl-L-tyrosine ethyl ester. Its ability to interact with hydrogen peroxide was evaluated by light emission in the presence of a perylene activator. Its cytotoxicity is three times less than that of bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate (CPPO).

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