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Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol

, 
Vitaliy Vladimirovich Andriyashin 1
Vitaliy Vladimirovich Andriyashin
, 
Semyon Romanovich Romanov 1
Semyon Romanovich Romanov
, 
Svetlana Nikolaevna Egorova 2
Svetlana Nikolaevna Egorova
, 
Nataliya Vladimirovna Vorob'eva 2
Nataliya Vladimirovna Vorob'eva
, 
Marina Petrovna Shulaeva 3
Marina Petrovna Shulaeva
, 
Oskar Kimovich Pozdeev 3
Oskar Kimovich Pozdeev
, 
Igor Anatol'evich Litvinov 4
Igor Anatol'evich Litvinov
, 
1 Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation
2 Kazan State Medical University, Kazan, Russian Federation
3 Kazan State Medical Academy, Kazan, Russian Federation
4 A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
10.1016/j.mencom.2023.09.014
Published 2023-09-01
Communication , Volume 33, Issue 5, 635-637
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Galkina I. V. et al. Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol // Mendeleev Communications. 2023. Vol. 33. No. 5. pp. 635-637.
GOST all authors (up to 50) Copy
Galkina I. V., Andriyashin V. V., Romanov S. R., Egorova S. N., Vorob'eva N. V., Shulaeva M. P., Pozdeev O. K., Litvinov I. A., Bakhtiyarova Y. V. Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol // Mendeleev Communications. 2023. Vol. 33. No. 5. pp. 635-637.
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TY - JOUR
DO - 10.1016/j.mencom.2023.09.014
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.09.014
TI - Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol
T2 - Mendeleev Communications
AU - Galkina, Irina Vasilievna
AU - Andriyashin, Vitaliy Vladimirovich
AU - Romanov, Semyon Romanovich
AU - Egorova, Svetlana Nikolaevna
AU - Vorob'eva, Nataliya Vladimirovna
AU - Shulaeva, Marina Petrovna
AU - Pozdeev, Oskar Kimovich
AU - Litvinov, Igor Anatol'evich
AU - Bakhtiyarova, Yulia Valerievna
PY - 2023
DA - 2023/09/01
PB - Mendeleev Communications
SP - 635-637
IS - 5
VL - 33
ER -
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@article{2023_Galkina,
author = {Irina Vasilievna Galkina and Vitaliy Vladimirovich Andriyashin and Semyon Romanovich Romanov and Svetlana Nikolaevna Egorova and Nataliya Vladimirovna Vorob'eva and Marina Petrovna Shulaeva and Oskar Kimovich Pozdeev and Igor Anatol'evich Litvinov and Yulia Valerievna Bakhtiyarova},
title = {Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.09.014},
number = {5},
pages = {635--637},
doi = {10.1016/j.mencom.2023.09.014}
}
MLA
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Galkina, Irina Vasilievna, et al. “Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol.” Mendeleev Communications, vol. 33, no. 5, Sep. 2023, pp. 635-637. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.09.014.

Keywords

2
6-di-tert-butyl-4-methylphenol
Antibacterial activity
antifungal activity.
quaternary phosphonium salts
sterically hindered phenols

Abstract

New biologically active quaternary bis-phosphonium salts were obtained by quaternization of 4-bromomethyl-2,6-di-tert-butylphenol with several α,ω,-bis(diphenylphosphino)-alkanes. All synthesized compounds demonstrated high antibacterial and antifungal activities against pathogenic microflora of humans and animals.

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