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Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody

Anna Sergeevna Efimova 1, 2
Anna Sergeevna Efimova
,  , 
Margarita Alekseevna Maksimova 1, 3, 4
Margarita Alekseevna Maksimova
, 
Anastasya Yuryevna Frolova 1, 3
Anastasya Yuryevna Frolova
, 
Vladimir Ivanovich Martynov 3
Vladimir Ivanovich Martynov
, 
Sergey Mikhailovich Deyev 3
Sergey Mikhailovich Deyev
, 
Alexey Alexandrovich Pakhomov 1, 3
Alexey Alexandrovich Pakhomov
, 
Yurii Viktorovich Fedorov 1
Yurii Viktorovich Fedorov
, 
Olga Anatol'evna Fedorova 1, 2
Olga Anatol'evna Fedorova
1 A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
2 D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
3 M.M. Shemyakin-Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
4 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
10.1016/j.mencom.2023.04.027
Published 2023-04-13
Communication , Volume 33, Issue 3, 384-386
7
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Efimova A. S. et al. Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody // Mendeleev Communications. 2023. Vol. 33. No. 3. pp. 384-386.
GOST all authors (up to 50) Copy
Efimova A. S., Ustimova M. A., Maksimova M. A., Frolova A. Y., Martynov V. I., Deyev S. M., Pakhomov A. A., Fedorov Y. V., Fedorova O. A. Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody // Mendeleev Communications. 2023. Vol. 33. No. 3. pp. 384-386.
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TY - JOUR
DO - 10.1016/j.mencom.2023.04.027
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.027
TI - Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody
T2 - Mendeleev Communications
AU - Efimova, Anna Sergeevna
AU - Ustimova, Mariya Alekseevna
AU - Maksimova, Margarita Alekseevna
AU - Frolova, Anastasya Yuryevna
AU - Martynov, Vladimir Ivanovich
AU - Deyev, Sergey Mikhailovich
AU - Pakhomov, Alexey Alexandrovich
AU - Fedorov, Yurii Viktorovich
AU - Fedorova, Olga Anatol'evna
PY - 2023
DA - 2023/04/13
PB - Mendeleev Communications
SP - 384-386
IS - 3
VL - 33
ER -
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@article{2023_Efimova,
author = {Anna Sergeevna Efimova and Mariya Alekseevna Ustimova and Margarita Alekseevna Maksimova and Anastasya Yuryevna Frolova and Vladimir Ivanovich Martynov and Sergey Mikhailovich Deyev and Alexey Alexandrovich Pakhomov and Yurii Viktorovich Fedorov and Olga Anatol'evna Fedorova},
title = {Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.027},
number = {3},
pages = {384--386},
doi = {10.1016/j.mencom.2023.04.027}
}
MLA
Cite this
MLA Copy
Efimova, Anna Sergeevna, et al. “Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody.” Mendeleev Communications, vol. 33, no. 3, Apr. 2023, pp. 384-386. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.04.027.

Keywords

antibody
covalent labeling
fluorescent probes
protein
pyridinium salts.
styryl dyes

Abstract

Two new styryl-type dyes modified with the succinimide ester group were prepared for conjugation with antibodies. The optical characteristics of the obtained compounds in different solvents were studied, and the solvatochromic properties of these dyes were revealed. The applicability of the dyes as protein labels was demonstrated in cyto-fluorometry and fluorescence microscopy.

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