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Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids

Semyon Romanovich Romanov 1
Semyon Romanovich Romanov
,  , 
Marina Petrovna Shulaeva 2
Marina Petrovna Shulaeva
, 
Oskar Kimovich Pozdeev 2
Oskar Kimovich Pozdeev
, 
Daut Rinatovich Islamov 1
Daut Rinatovich Islamov
,  , 
1 Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation
2 Kazan State Medical Academy, Kazan, Russian Federation
10.1016/j.mencom.2023.02.032
Published 2023-02-13
Communication , Volume 33, Issue 2, 249-251
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Romanov S. R. et al. Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 249-251.
GOST all authors (up to 50) Copy
Romanov S. R., Shibaeva K. O., Shulaeva M. P., Pozdeev O. K., Islamov D. R., Galkina I. V., Bakhtiyarova Y. V. Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 249-251.
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TY - JOUR
DO - 10.1016/j.mencom.2023.02.032
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.032
TI - Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids
T2 - Mendeleev Communications
AU - Romanov, Semyon Romanovich
AU - Shibaeva, Karina Olegovna
AU - Shulaeva, Marina Petrovna
AU - Pozdeev, Oskar Kimovich
AU - Islamov, Daut Rinatovich
AU - Galkina, Irina Vasilievna
AU - Bakhtiyarova, Yulia Valerievna
PY - 2023
DA - 2023/02/13
PB - Mendeleev Communications
SP - 249-251
IS - 2
VL - 33
ER -
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@article{2023_Romanov,
author = {Semyon Romanovich Romanov and Karina Olegovna Shibaeva and Marina Petrovna Shulaeva and Oskar Kimovich Pozdeev and Daut Rinatovich Islamov and Irina Vasilievna Galkina and Yulia Valerievna Bakhtiyarova},
title = {Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.032},
number = {2},
pages = {249--251},
doi = {10.1016/j.mencom.2023.02.032}
}
MLA
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Romanov, Semyon Romanovich, et al. “Synthesis of arsonium salts and betaines based on triphenylarsine and ω-bromoalkanoic acids.” Mendeleev Communications, vol. 33, no. 2, Feb. 2023, pp. 249-251. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.032.

Keywords

antitumor agents
arsenobetaines
arsonium salts
biological activity
carboxylic acids
organoarsenic compounds.
phosphobetaine
phosphonium salts

Abstract

The reactions between Ph3As and ω-bromoalkanoic acids with the length of polymethylene fragment n = 5, 7, 9 afford quaternary arsonium salts. Their treatment with alkali gives biologically active arsenobetaines. Solvent-free reactions of Ph3P or Ph3As with 2,3-dibromopropionic acid lead to the corresponding arsonium and phosphonium salts bearing (CH2)2COOH substituent.

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