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Multi-compartment containers from a mixture of natural and synthetic lipids

Aleksandr Anatol'evich Yaroslavov 1
Aleksandr Anatol'evich Yaroslavov
, 
Anna Aleksandrovna Efimova 1
Anna Aleksandrovna Efimova
, 
Tatiana Aleksandrovna Abramova 1
Tatiana Aleksandrovna Abramova
,  , 
Vladimir Izrailevich Muronetz 2
Vladimir Izrailevich Muronetz
1 Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
2 A.N. Belozersky Research Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
10.1016/j.mencom.2023.02.023
Published 2023-02-13
Communication , Volume 33, Issue 2, 221-224
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Yaroslavov A. A. et al. Multi-compartment containers from a mixture of natural and synthetic lipids // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 221-224.
GOST all authors (up to 50) Copy
Yaroslavov A. A., Efimova A. A., Abramova T. A., Pozdyshev D. V., Muronetz V. I. Multi-compartment containers from a mixture of natural and synthetic lipids // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 221-224.
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TY - JOUR
DO - 10.1016/j.mencom.2023.02.023
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.023
TI - Multi-compartment containers from a mixture of natural and synthetic lipids
T2 - Mendeleev Communications
AU - Yaroslavov, Aleksandr Anatol'evich
AU - Efimova, Anna Aleksandrovna
AU - Abramova, Tatiana Aleksandrovna
AU - Pozdyshev, Denis Valerievich
AU - Muronetz, Vladimir Izrailevich
PY - 2023
DA - 2023/02/13
PB - Mendeleev Communications
SP - 221-224
IS - 2
VL - 33
ER -
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@article{2023_Yaroslavov,
author = {Aleksandr Anatol'evich Yaroslavov and Anna Aleksandrovna Efimova and Tatiana Aleksandrovna Abramova and Denis Valerievich Pozdyshev and Vladimir Izrailevich Muronetz},
title = {Multi-compartment containers from a mixture of natural and synthetic lipids},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.023},
number = {2},
pages = {221--224},
doi = {10.1016/j.mencom.2023.02.023}
}
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Yaroslavov, Aleksandr Anatol'evich, et al. “Multi-compartment containers from a mixture of natural and synthetic lipids.” Mendeleev Communications, vol. 33, no. 2, Feb. 2023, pp. 221-224. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.02.023.

Keywords

biodegradation
cytotoxicity.
liposome
multi-compartment container
multi-liposomal complex

Abstract

Small anionic liposomes were electrostatically adsorbed on the surface of larger cationic liposomes thus forming multi- compartment complexes composed exclusively of natural and synthetic lipids. The complexes contained two dozen anionic liposomes per a single cationic liposome and showed low cytotoxicity and ability to enzyme-induced bio-degradation. The liposomal multi-compartment complexes demonstrate great application potential as containers for drug encapsulation and delivery.

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