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Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies

Galina Valentinovna Pazynina 1
Galina Valentinovna Pazynina
Svetlana Vladimirovna Tsygankova 1
Svetlana Vladimirovna Tsygankova
Marina Aleksandrovna Sablina 1
Marina Aleksandrovna Sablina
Nadezhda Vladimirovna Shilova 1, 2
Nadezhda Vladimirovna Shilova
Alexander Sergeyevich Paramonov
Alexander Olegovich Chizhov 3
Alexander Olegovich Chizhov
Nicolai Vladimirovich Bovin 1
Nicolai Vladimirovich Bovin
1 M.M. Shemyakin-Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
2 National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, Russian Federation
Published 2022-12-26
CommunicationVolume 33, Issue 1, 107-108
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Pazynina G. V. et al. Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies // Mendeleev Communications. 2022. Vol. 33. No. 1. pp. 107-108.
GOST all authors (up to 50) Copy
Pazynina G. V., Tsygankova S. V., Sablina M. A., Shilova N. V., Paramonov A. S., Chizhov A. O., Bovin N. V. Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies // Mendeleev Communications. 2022. Vol. 33. No. 1. pp. 107-108.
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TY - JOUR
DO - 10.1016/j.mencom.2023.01.033
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.033
TI - Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies
T2 - Mendeleev Communications
AU - Pazynina, Galina Valentinovna
AU - Tsygankova, Svetlana Vladimirovna
AU - Sablina, Marina Aleksandrovna
AU - Shilova, Nadezhda Vladimirovna
AU - Paramonov, Alexander Sergeyevich
AU - Chizhov, Alexander Olegovich
AU - Bovin, Nicolai Vladimirovich
PY - 2022
DA - 2022/12/26
PB - Mendeleev Communications
SP - 107-108
IS - 1
VL - 33
ER -
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@article{2022_Pazynina,
author = {Galina Valentinovna Pazynina and Svetlana Vladimirovna Tsygankova and Marina Aleksandrovna Sablina and Nadezhda Vladimirovna Shilova and Alexander Sergeyevich Paramonov and Alexander Olegovich Chizhov and Nicolai Vladimirovich Bovin},
title = {Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies},
journal = {Mendeleev Communications},
year = {2022},
volume = {33},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.033},
number = {1},
pages = {107--108},
doi = {10.1016/j.mencom.2023.01.033}
}
MLA
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Pazynina, Galina Valentinovna, et al. “Synthesis of Sug1-4GalNAcα disaccharides and their interaction with human blood antibodies.” Mendeleev Communications, vol. 33, no. 1, Dec. 2022, pp. 107-108. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.033.
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Keywords

anti-glycan antibodies
antigen
glycan synthesis
glycosylation
printed glycan array (PGA).

Abstract

Disaccharides Sug1-4GalNAcα-Osp (Sug = Gal, Glc, GalNAc, GlcNAc in α- or β-configuration) were synthesized as spacer (sp) glycosides. Their strong interaction with serum antibodies of healthy donors was demonstrated using a printed glycan array (PGA).

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