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One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers

Elena Borisovna Rakhimova 1
Elena Borisovna Rakhimova
,  , 
Ulyana Sh Kuzmina 2
Ulyana Sh Kuzmina
, 
Yulia Venerovna Vakhitova 2
Yulia Venerovna Vakhitova
1 Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
2 Institute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa, Russian Federation
10.1016/j.mencom.2023.01.020
Published 2022-12-26
Communication , Volume 33, Issue 1, 64-66
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Rakhimova E. B. et al. One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers // Mendeleev Communications. 2022. Vol. 33. No. 1. pp. 64-66.
GOST all authors (up to 50) Copy
Rakhimova E. B., Kirsanov V. Y., Kuzmina U. S., Vakhitova Y. V. One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers // Mendeleev Communications. 2022. Vol. 33. No. 1. pp. 64-66.
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TY - JOUR
DO - 10.1016/j.mencom.2023.01.020
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.020
TI - One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers
T2 - Mendeleev Communications
AU - Rakhimova, Elena Borisovna
AU - Kirsanov, Victor Yuryevich
AU - Kuzmina, Ulyana Sh
AU - Vakhitova, Yulia Venerovna
PY - 2022
DA - 2022/12/26
PB - Mendeleev Communications
SP - 64-66
IS - 1
VL - 33
ER -
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@article{2022_Rakhimova,
author = {Elena Borisovna Rakhimova and Victor Yuryevich Kirsanov and Ulyana Sh Kuzmina and Yulia Venerovna Vakhitova},
title = {One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers},
journal = {Mendeleev Communications},
year = {2022},
volume = {33},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.020},
number = {1},
pages = {64--66},
doi = {10.1016/j.mencom.2023.01.020}
}
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Rakhimova, Elena Borisovna, et al. “One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers.” Mendeleev Communications, vol. 33, no. 1, Dec. 2022, pp. 64-66. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2023.01.020.
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Keywords

cytotoxic activity.
heterocyclization
maleopimaric acid
Polycycles
terpenoids
zeolite

Abstract

Novel terpenoid dimers linked through the E-E rings were synthesized by catalytic multicomponent condensation of amino derivatives of methyl maleopimarate with form-aldehyde and dimethyl-tetraazadecalin or tetraazaperhydro- tetracene. Primary screening of the synthesized terpenoid dimers for cytotoxic activity was performed.

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