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Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity

Anton Romanovich Egorov 1
Anton Romanovich Egorov
, 
Margarita Nikolaevna Kurasova 1
Margarita Nikolaevna Kurasova
, 
Omar Muslimovich Khubiev 1
Omar Muslimovich Khubiev
, 
Nikita A Bogdanov 1
Nikita A Bogdanov
, 
Alexander G Tskhovrebov 1
Alexander G Tskhovrebov
, 
Analoly Aleksandrovich Kirichuk 1
Analoly Aleksandrovich Kirichuk
, 
Victor Nikolaevich Khrustalev 1, 2
Victor Nikolaevich Khrustalev
, 
Vasili V Rubanik 3
Vasili V Rubanik
, 
Vasili V.,Jr. Rubanik 3
Vasili V.,Jr. Rubanik
, 
Andreii Sergeevich Kritchenkov 1, 3
Andreii Sergeevich Kritchenkov
10.1016/j.mencom.2022.11.022
Published 2022-10-21
Communication , Volume 32, Issue 6, 774-776
7
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Egorov A. R. et al. Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity // Mendeleev Communications. 2022. Vol. 32. No. 6. pp. 774-776.
GOST all authors (up to 50) Copy
Egorov A. R., Kurasova M. N., Khubiev O. M., Bogdanov N. A., Tskhovrebov A. G., Kirichuk A. A., Khrustalev V. N., Rubanik V. V., Rubanik V. V., Kritchenkov A. S. Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity // Mendeleev Communications. 2022. Vol. 32. No. 6. pp. 774-776.
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TY - JOUR
DO - 10.1016/j.mencom.2022.11.022
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.11.022
TI - Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity
T2 - Mendeleev Communications
AU - Egorov, Anton Romanovich
AU - Kurasova, Margarita Nikolaevna
AU - Khubiev, Omar Muslimovich
AU - Bogdanov, Nikita A
AU - Tskhovrebov, Alexander G
AU - Kirichuk, Analoly Aleksandrovich
AU - Khrustalev, Victor Nikolaevich
AU - Rubanik, Vasili V
AU - Rubanik, Vasili V.,Jr.
AU - Kritchenkov, Andreii Sergeevich
PY - 2022
DA - 2022/10/21
PB - Mendeleev Communications
SP - 774-776
IS - 6
VL - 32
ER -
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@article{2022_Egorov,
author = {Anton Romanovich Egorov and Margarita Nikolaevna Kurasova and Omar Muslimovich Khubiev and Nikita A Bogdanov and Alexander G Tskhovrebov and Analoly Aleksandrovich Kirichuk and Victor Nikolaevich Khrustalev and Vasili V Rubanik and Vasili V.,Jr. Rubanik and Andreii Sergeevich Kritchenkov},
title = {Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.11.022},
number = {6},
pages = {774--776},
doi = {10.1016/j.mencom.2022.11.022}
}
MLA
Cite this
MLA Copy
Egorov, Anton Romanovich, et al. “Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity.” Mendeleev Communications, vol. 32, no. 6, Oct. 2022, pp. 774-776. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.11.022.

Keywords

Antibacterial activity
carboxamides
chitosan
ciprofloxacin
conjugates
toxicity
ultrasound treatment

Abstract

Ultrasound-mediated reaction of chitosan with ciprofloxacin in the presence of N,N'-dicyclohexylcarbodiimide in water gives the chitosan–ciprofloxacin conjugates of carboxamide type. The conjugates show a mediate antibacterial effect and reduced cytotoxicity.

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