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Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles

Yana Yur'evna Shmoylova 1
Yana Yur'evna Shmoylova
, 
Yuri Alexandrovich Kovygin 1
Yuri Alexandrovich Kovygin
, 
Evgeniya Andreevna Kosheleva 1
Evgeniya Andreevna Kosheleva
, 
Khidmet Sapharovich Shikhaliev 1
Khidmet Sapharovich Shikhaliev
, 
Irina Vladimirovna Ledenyova 1
Irina Vladimirovna Ledenyova
, 
Mikhail Avramovich Prezent 2
Mikhail Avramovich Prezent
10.1016/j.mencom.2022.09.041
Published 2022-09-05
Communication , Volume 32, Issue 5, 688-690
8
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Shmoylova Y. Y. et al. Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 688-690.
GOST all authors (up to 50) Copy
Shmoylova Y. Y., Kovygin Y. A., Kosheleva E. A., Shikhaliev K. S., Ledenyova I. V., Prezent M. A. Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 688-690.
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TY - JOUR
DO - 10.1016/j.mencom.2022.09.041
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.09.041
TI - Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles
T2 - Mendeleev Communications
AU - Shmoylova, Yana Yur'evna
AU - Kovygin, Yuri Alexandrovich
AU - Kosheleva, Evgeniya Andreevna
AU - Shikhaliev, Khidmet Sapharovich
AU - Ledenyova, Irina Vladimirovna
AU - Prezent, Mikhail Avramovich
PY - 2022
DA - 2022/09/05
PB - Mendeleev Communications
SP - 688-690
IS - 5
VL - 32
ER -
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@article{2022_Shmoylova,
author = {Yana Yur'evna Shmoylova and Yuri Alexandrovich Kovygin and Evgeniya Andreevna Kosheleva and Khidmet Sapharovich Shikhaliev and Irina Vladimirovna Ledenyova and Mikhail Avramovich Prezent},
title = {Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.09.041},
number = {5},
pages = {688--690},
doi = {10.1016/j.mencom.2022.09.041}
}
MLA
Cite this
MLA Copy
Shmoylova, Yana Yur'evna, et al. “Efficient synthesis of tetrahydro-1H-pyrazolo[3,4-b]pyridines based on the recyclization of N-arylitaconimides with aminopyrazoles.” Mendeleev Communications, vol. 32, no. 5, Sep. 2022, pp. 688-690. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.09.041.

Keywords

5-aminopyrazoles
chemoselectivity
heterocyclization
itaconimides
pyrazolo[3,4-b]pyridines
recyclization

Abstract

New polyfunctional hydrogenated pyrazolo[3,4-b]pyridines were obtained by the chemoselective reaction between N-arylitaconimides and 5-aminopyrazoles. The transformation is the cascade reaction including Michael addition at the active double bond of the itaconimide followed by the intramolecular transamidation and recyclization.

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