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Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives

Konstantin Evgen'evich Shepelenko 1
Konstantin Evgen'evich Shepelenko
, 
Ksenia Alekseevna Nikolaeva 1
Ksenia Alekseevna Nikolaeva
, 
Irina Gennad'evna Gnatiuk 1
Irina Gennad'evna Gnatiuk
, 
Olga Gennad'evna Garanzha 1
Olga Gennad'evna Garanzha
, 
Andrey Anatol'evich Alexandrov 1
Andrey Anatol'evich Alexandrov
,  , 
Viktor Mikhailovich Chernyshev 1
Viktor Mikhailovich Chernyshev
10.1016/j.mencom.2022.07.018
Published 2022-07-01
Communication , Volume 32, Issue 4, 485-487
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Shepelenko K. E. et al. Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives // Mendeleev Communications. 2022. Vol. 32. No. 4. pp. 485-487.
GOST all authors (up to 50) Copy
Shepelenko K. E., Nikolaeva K. A., Gnatiuk I. G., Garanzha O. G., Alexandrov A. A., Minyaev M. E., Chernyshev V. M. Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives // Mendeleev Communications. 2022. Vol. 32. No. 4. pp. 485-487.
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TY - JOUR
DO - 10.1016/j.mencom.2022.07.018
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.07.018
TI - Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives
T2 - Mendeleev Communications
AU - Shepelenko, Konstantin Evgen'evich
AU - Nikolaeva, Ksenia Alekseevna
AU - Gnatiuk, Irina Gennad'evna
AU - Garanzha, Olga Gennad'evna
AU - Alexandrov, Andrey Anatol'evich
AU - Minyaev, Mikhail Evgenievich
AU - Chernyshev, Viktor Mikhailovich
PY - 2022
DA - 2022/07/01
PB - Mendeleev Communications
SP - 485-487
IS - 4
VL - 32
ER -
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@article{2022_Shepelenko,
author = {Konstantin Evgen'evich Shepelenko and Ksenia Alekseevna Nikolaeva and Irina Gennad'evna Gnatiuk and Olga Gennad'evna Garanzha and Andrey Anatol'evich Alexandrov and Mikhail Evgenievich Minyaev and Viktor Mikhailovich Chernyshev},
title = {Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.07.018},
number = {4},
pages = {485--487},
doi = {10.1016/j.mencom.2022.07.018}
}
MLA
Cite this
MLA Copy
Shepelenko, Konstantin Evgen'evich, et al. “Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives.” Mendeleev Communications, vol. 32, no. 4, Jul. 2022, pp. 485-487. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.07.018.

Keywords

2-hetarylfurans
arylation
benzimidazoles
carboxylate assistance
CH-functionalization
furans
ruthenium complexes

Abstract

An efficient selective C(3)–H arylation of furan ring in 2-(furan-2-yl)benzimidazoles, derivatives of fuberidazole fungicide, with aryl bromides catalyzed by [RuCl2(cymene)]2/ pivalic acid system has been accomplished. High selectivity of the process may be accounted for by the action of benzimidazol-2-yl substituent as the directing group.

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